Efficient microwave-assisted one-pot three-component synthesis of 2,3-disubstituted benzofurans under Sonogashira conditions was written by Markina, Nataliya A.;Chen, Yu;Larock, Richard C.. And the article was included in Tetrahedron in 2013.HPLC of Formula: 207115-22-8 This article mentions the following:
An efficient one-pot method for the synthesis of 2,3-disubstituted benzo[b]furans from com. available 2-iodophenols, terminal acetylenes and aryl iodides has been developed utilizing Sonogashira reaction conditions. After an initial Sonogashira coupling of the 2-iodophenol with the terminal alkyne, cyclization involving the aryl iodide provides the 2,3-disubstituted benzo[b]furans, e.g., I, in good to excellent yields. The use of microwave irradiation shortens the reaction times and minimizes the side products. This methodol. is especially useful for the construction of libraries of highly substituted benzo[b]furans and their analogs. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8HPLC of Formula: 207115-22-8).
4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.HPLC of Formula: 207115-22-8
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com