Palladium-catalyzed C(sp3)-H arylation of lactic acid: efficient synthesis of chiral β-aryl-α-hydroxy acids was written by Chen, Kai;Li, Xin;Zhang, Shuo-Qing;Shi, Bing-Feng. And the article was included in Organic Chemistry Frontiers in 2016.Recommanded Product: 4-Iodo-1,2-dimethoxybenzene This article mentions the following:
Pd-catalyzed enantioselective arylation of lactic acid substrates employing 8-aminoquinoline as the directing group was reported. The protocol was found to be compatible with a broad range of synthetically useful functional groups, thus providing a practical route to chiral aryl-alkoxy-N-(quinolinyl)propanamides, e.g., I. Further, the new reaction was also applied to the synthesis of pharmaceutically important α-hydroxy acids, such as LY519818 and tesaglitazar. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Recommanded Product: 4-Iodo-1,2-dimethoxybenzene).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Recommanded Product: 4-Iodo-1,2-dimethoxybenzene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com