Synthesis of gem-difluoromethylenated biflavonoid via the Suzuki coupling reaction was written by Zheng, Xing;Meng, Wei-Dong;Qing, Feng-Ling. And the article was included in Tetrahedron Letters in 2004.Computed Properties of C8H7IO2 This article mentions the following:
Gem-Difluoromethylenated biflavonoid I was synthesized via the Suzuki coupling reaction. The key intermediate 6-iodinated flavone was regioselectively synthesized by the use of AgOAc/I2 under mild conditions without handling of a strongly toxic reagent. The key step was the formation of a flavone 3′-boronate using a palladium-catalyzed exchange of the corresponding 3′-iodinated flavone with a diboron reagent. In the experiment, the researchers used many compounds, for example, 3-Iodo-4-methoxybenzaldehyde (cas: 2314-37-6Computed Properties of C8H7IO2).
3-Iodo-4-methoxybenzaldehyde (cas: 2314-37-6) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Computed Properties of C8H7IO2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com