Bergman cycloaromatization of imidazole-fused enediynes: the remarkable effect of N-aryl substitution was written by Zhao, Zhengrong;Peng, Yunshan;Dalley, N. Kent;Cannon, John F.;Peterson, Matt A.. And the article was included in Tetrahedron Letters in 2004.Recommanded Product: 4,5-Diiodo-1H-imidazole This article mentions the following:
A series of N-aryl-substituted ‘imidazole-fused’ (Z) 3-ene-1,5-diynes, e.g., I, was prepared and kinetic parameters for their Bergman cycloaromatization reactivities were determined N-Arylation enhanced rates relative to N-alkyl derivatives by up to sevenfold (ANOVA p<0.0001). The greatest enhancement was exhibited by I. In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Recommanded Product: 4,5-Diiodo-1H-imidazole).
4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Recommanded Product: 4,5-Diiodo-1H-imidazole
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com