Dehydroxyalkylative halogenation of C(aryl)-C bonds of aryl alcohols was written by Liu, Mingyang;Zhang, Zhanrong;Liu, Huizhen;Wu, Tianbin;Han, Buxing. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020.Name: 4-Chloro-2-iodo-1-nitrobenzene This article mentions the following:
Synthesis of aromatic halogen compounds Ar-X [Ar = 2-O2NC6H4, 2-furyl, 2-thienyl, etc.; X = Cl, Br, I] were prepared using environmentally benign mol. oxygen as oxidant and Cu-based catalysts-mediated side-directed dehydroxyalkylative halogenation of aryl alcs. C(aryl)-C bonds of aryl alcs. were effectively cleaved and afforded the corresponding aryl chlorides, bromides and iodides in excellent yields. Aryl alcs. could served as both aromatic electrophilic and radical synthetic equivalent during the reaction. In the experiment, the researchers used many compounds, for example, 4-Chloro-2-iodo-1-nitrobenzene (cas: 160938-18-1Name: 4-Chloro-2-iodo-1-nitrobenzene).
4-Chloro-2-iodo-1-nitrobenzene (cas: 160938-18-1) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Name: 4-Chloro-2-iodo-1-nitrobenzene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com