Solid-phase total synthesis of scytalidamide A was written by Gu, Wenxin;Silverman, Richard B.. And the article was included in Journal of Organic Chemistry in 2003.Safety of 3-Iodo-4-methoxybenzaldehyde This article mentions the following:
The first total synthesis of the natural cyclic heptapeptide scytalidamide A was achieved on solid phase using two different linker resins, a phenylalanine silane resin and a 4-methoxybenzaldehyde backbone linker resin. The synthetic product confirms the structure of the natural product reported in the preceding paper in this issue (Tan, L. T. at al.). In the experiment, the researchers used many compounds, for example, 3-Iodo-4-methoxybenzaldehyde (cas: 2314-37-6Safety of 3-Iodo-4-methoxybenzaldehyde).
3-Iodo-4-methoxybenzaldehyde (cas: 2314-37-6) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I. This periodic order also follows the atomic radius of halogens and the length of the carbon-halogen bond.Safety of 3-Iodo-4-methoxybenzaldehyde
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com