Ortholithiation of unprotected benzoic acids: application for novel 2-chloro-6-substituted benzoic acid syntheses was written by Gohier, Frederic;Castanet, Anne-Sophie;Mortier, Jacques. And the article was included in Synthetic Communications in 2005.Formula: C7H4ClIO2 This article mentions the following:
2-Chloro-6-substituted benzoic acids were prepared by the tandem metalation sequence from 2-chlorobenzoic acid with the 1:1 complex sec-butyllithium/TMEDA in THF at -78°C followed by quenching with electrophiles. In the experiment, the researchers used many compounds, for example, 2-Chloro-6-iodobenzoic acid (cas: 13420-63-8Formula: C7H4ClIO2).
2-Chloro-6-iodobenzoic acid (cas: 13420-63-8) belongs to iodide derivatives. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Formula: C7H4ClIO2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com