K2S2O8-promoted [2+2]-cycloaddition of benzyl-2-(3-hydroxypropynyl)-benzoates: A new route to polysubstituted cyclobutanes was written by Zhu, Hai-Tao;Tong, Xiao-Juan;Zhou, Ni-Ni;Yang, De-Suo;Fan, Ming-Jin. And the article was included in Tetrahedron Letters in 2016.Reference of 13420-63-8 This article mentions the following:
An efficient and convenient metal-free [2+2]-cycloaddition of benzyl-2-(3-hydroxypropynyl)-benzoates via allene processes was developed, which provides impressive access to fused cyclobutanes from easily accessed π-components. This transformation involved the cleavage of two C-O bonds, the formations of two C-O bonds and two C-C bonds and showed some advantages, including mild conditions and wide substrate scope. In the experiment, the researchers used many compounds, for example, 2-Chloro-6-iodobenzoic acid (cas: 13420-63-8Reference of 13420-63-8).
2-Chloro-6-iodobenzoic acid (cas: 13420-63-8) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Iodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Reference of 13420-63-8
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com