Approach to phenanthroindolizidine alkaloids using organic azides with 1-aryl allylic alcohols: Unexpected tandem reactions to indenyl aziridines via Nazarov cyclization was written by Yokoi, Taiki;Sugiura, Takahiro;Tanimoto, Hiroki;Morimoto, Tsumoru;Nishiyama, Yasuhiro;Kakiuchi, Kiyomi. And the article was included in Heterocycles in 2016.Electric Literature of C8H9IO2 This article mentions the following:
Organic azide cyclization reactions with 1-aryl allylic alcs. were investigated in a synthetic study of phenanthroindolizidine alkaloids. Unsaturated imines (enimines) were effectively obtained from the allylic alc. adjacent to electron-rich aromatic rings under thermal reaction conditions. The tandem aziridination-Nazarov reactions to indenyl aziridines were preferred to the acid-mediated enimine formation via Schmidt reaction in the case of 3-aryl diallylic alcs. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Electric Literature of C8H9IO2).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Electric Literature of C8H9IO2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com