Longobardo, Luigi et al. published their research in SpringerPlus in 2015 | CAS: 10297-05-9

A practical route to β^2,3-amino acids with alkyl side chains was written by Longobardo, Luigi;DellaGreca, Marina;de Paola, Ivan. And the article was included in SpringerPlus in 2015.Synthetic Route of C4H8ClI This article mentions the following:

Enantiopure N(Boc)-β³-amino nitriles, valuable synthetic intermediates in the multistep homologation of α-amino acids, were alkylated using n-BuLi as base. Alkylations afforded easily separable, almost equimol. mixtures of diastereomeric N(Boc)-protected syn and anti β^2,3-amino nitriles. Suitable manipulations of both cyano and amino groups eventually led to enantiopure N- and/or C-protected β^2,3-amino acids. For example, methanolysis using concentrate HCl gas in MeOH, provides C-protected β^2,3-amino acids in excellent yields. This methodol. is applied to the synthesis of a series N(Boc)-β^2,3-dialkyl amino nitriles derived from L-phenylalanine, D-phenylalanine, L-valine and one C-protected β^2,3-amino acid. The authors demonstrate an efficient procedure for the preparation of anti and syn β^2,3-amino acids with alkyl side chains, from α-amino acids in reasonable yields. In the experiment, the researchers used many compounds, for example, 1-Chloro-4-iodobutane (cas: 10297-05-9Synthetic Route of C4H8ClI).

1-Chloro-4-iodobutane (cas: 10297-05-9) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Synthetic Route of C4H8ClI

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com