Liu, Zhenghui et al. published their research in RSC Advances in 2020 | CAS: 22918-03-2

4-Chloro-2-iodopyridine (cas: 22918-03-2) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Recommanded Product: 22918-03-2

Small organic molecules with tailored structures: initiators in the transition-metal-free C-H arylation of unactivated arenes was written by Liu, Zhenghui;Wang, Peng;Chen, Yu;Yan, Zhenzhong;Chen, Suqing;Chen, Wenjun;Mu, Tiancheng. And the article was included in RSC Advances in 2020.Recommanded Product: 22918-03-2 This article mentions the following:

In this article, an optimized catalytically active mol., (2-(methylamino)phenyl)methanol, was designed. A broad range of aryl iodides RI (R = 2-fluorophenyl, thiophen-3-yl, pyridin-4-yl, etc.) could be converted into the corresponding arylated products RR1 (R1 = Ph, 4-methylphenyl) at 100°C over 24 h with good to excellent yields. Mechanistic experiments verified that radicals participated in this catalytic transformation and that the cleavage of the aromatic C-H bond was not the rate determining step. A K+ capture experiment by 18-crown-6 emphasized the significance of the cation species of the strong base. Fourier transform IR spectroscopy proved that the catalytic system was activated by the hydrogen bonds between small organic mols. and tBuOK. Also, a clear mechanism was proposed. This transition-metal-free method affords a promising system for efficient and inexpensive synthesis of biaryls via a user-friendly approach, as confirmed by scale-up experiments In the experiment, the researchers used many compounds, for example, 4-Chloro-2-iodopyridine (cas: 22918-03-2Recommanded Product: 22918-03-2).

4-Chloro-2-iodopyridine (cas: 22918-03-2) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Recommanded Product: 22918-03-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com