Triflic acid catalysed regioselective synthesis of substituted naphthalenes by benzannulation of carbonyls with alkynes was written by Gudla, Vanajakshi;Sudheer, Mokhamatam;Rao, Chinthu Joginarayana;Sanasi, Paul Douglas;Battula, Venkateswara Rao. And the article was included in Tetrahedron in 2021.Name: 4-Iodo-1,2-dimethoxybenzene This article mentions the following:
An interesting and facile triflic acid catalyzed annulation of α-aryl carbonyls with arylalkynes was presented for the regioselective synthesis of substituted naphthalenes. The annulation reaction involved a sequence of electrophilic attack of carbonyl on arylalkyne and benzannulation catalyzed by triflic acid. The present catalyst effects this transformation at room temperature itself. Intramol. version of the present Bronsted acid catalysis furnished compounds containing 1-arylnaphthalene core fused with ring systems in excellent yields. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Name: 4-Iodo-1,2-dimethoxybenzene).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.Name: 4-Iodo-1,2-dimethoxybenzene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com