Palladium catalysed 3-component cascade synthesis of bis(2-arylallyl) tertiary amines from aryl iodides, allene and primary amines was written by Gai, Xinjie;Grigg, Ronald;Collard, Simon;Muir, Jayne E.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2001.Recommanded Product: N,N-Diethyl-4-iodobenzamide This article mentions the following:
A 3-component cascade synthesis of bis(2-arylallyl) tertiary amines from aryl iodide, allene, and primary aliphatic amines is described. Chiral amines give analogous products with no detectable racemization. Mixtures of two different aryl iodides can be utilized to give the mixed tertiary amines as the sole, or major, product. The reaction is sensitive to stereoelectronic effects which lead to mono(2-arylallyl) secondary amines. In the experiment, the researchers used many compounds, for example, N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8Recommanded Product: N,N-Diethyl-4-iodobenzamide).
N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Recommanded Product: N,N-Diethyl-4-iodobenzamide
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com