Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships was written by Wallinder, Charlotta;Botros, Milad;Rosenstroem, Ulrika;Guimond, Marie-Odile;Beaudry, Helene;Nyberg, Fred;Gallo-Payet, Nicole;Hallberg, Anders;Alterman, Mathias. And the article was included in Bioorganic & Medicinal Chemistry in 2008.Recommanded Product: N,N-Diethyl-4-iodobenzamide This article mentions the following:
In the investigation of the structure-activity relationship of nonpeptide AT2 receptor agonists, a series of substituted benzamide analogs of the selective nonpeptide AT2 receptor agonist M024 have been synthesized. In a second series, the biphenyl scaffold was compared to the thienylphenyl scaffold and the impact of the iso-Bu substituent and its position on AT1/AT2 receptor selectivity was also investigated. Both series included several compounds with high affinity and selectivity for the AT2 receptor. Three of the compounds were also proven to function as agonists at the AT2 receptor, as deduced from a neurite outgrowth assay, conducted in NG108-15 cells. In the experiment, the researchers used many compounds, for example, N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8Recommanded Product: N,N-Diethyl-4-iodobenzamide).
N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Recommanded Product: N,N-Diethyl-4-iodobenzamide
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com