Reinvestigation of the orientation of halogen substitution in imidazoles by nuclear magnetic resonance spectroscopy was written by Naidu, M. Seshapathi R.;Bensusan, Howard B.. And the article was included in Journal of Organic Chemistry in 1968.Product Details of 15813-09-9 This article mentions the following:
Imidazole is treated with iodine at pH 7 and in an alk. medium and 4(5)-methylimidazole is treated with iodine in alk. medium to give 4,5-diiodoimidazole and 4(5)-iodo-5(4)-methylimidazole. Similarly prepared is 4(5)-bromo-5(4)-methylimidazole. N.M.R. data are given. In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Product Details of 15813-09-9).
4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Product Details of 15813-09-9
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com