Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus was written by Bahnous, Mebarek;Bouraiou, Abdelmalek;Chelghoum, Meryem;Bouacida, Sofiane;Roisnel, Thierry;Smati, Farida;Bentchouala, Chafia;Gros, Philippe C.;Belfaitah, Ali. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2013.Product Details of 15813-09-9 This article mentions the following:
Several new highly functionalized imidazolium derivatives were synthesized, via appropriate synthetic routes, using imidazole, 1-methylimidazole, and 2-phenyl-1-methylimidazole as key intermediates. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Salmonella thipymurium using disk-diffusion and MIC methods. Crystal X-ray structures are reported for six compounds In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Product Details of 15813-09-9).
4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Product Details of 15813-09-9
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com