Aberg, Ola et al. published their research in Journal of Labelled Compounds and Radiopharmaceuticals in 2010 | CAS: 77350-52-8

N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Safety of N,N-Diethyl-4-iodobenzamide

Synthesis and evaluation of a 11C-labelled angiotensin II AT2 receptor ligand was written by Aberg, Ola;Stevens, Marc;Lindh, Jonas;Wallinder, Charlotta;Hall, Hakan;Monazzam, Azita;Larhed, Mats;Langstrom, Bengt. And the article was included in Journal of Labelled Compounds and Radiopharmaceuticals in 2010.Safety of N,N-Diethyl-4-iodobenzamide This article mentions the following:

Three 11C-radiolabeled high-affinity nonpeptide AT2 receptor-selective ligands were synthesized, and one of these was evaluated as positron emission tomog. (PET) tracer. The labeling reaction was performed via Pd(0)-mediated aminocarbonylation of the aryl iodide substrate using 11CO as the labeled precursor. As an example, starting with 10.0 GBq 11CO, 1.10 GBq of the product N-butoxycarbonyl-3-[4-(N-benzyl-[11C]carbamoyl)phenyl]-5-isobutylthiophene-2-sulfonamide was obtained in 36% decay-corrected radiochem. yield (from 11CO), 42 min from end of bombardment with a specific activity of 110 GBq μmol-1. The N-isopropyl-[11C]carbamoyl analog (radiochem. purity >95%) was studied employing autoradiog., organ distribution, and small animal PET. In vitro autoradiog. showed specific binding in the pancreas and kidney. Organ distribution in rats revealed a high uptake in liver, intestine, kidney, and adrenals. Small animal PET showed rapid and reversible uptake in the kidneys followed by accumulation in the urinary bladder suggesting fast renal excretion of the tracer. In addition, high accumulation was also seen in the liver. In the experiment, the researchers used many compounds, for example, N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8Safety of N,N-Diethyl-4-iodobenzamide).

N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Safety of N,N-Diethyl-4-iodobenzamide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com