Month: December 2022

Xiao, Shouhua published the artcileInfluences of grafting on aromatic compounds in muskmelon by solid phase microextraction with GC-MS, Application In Synthesis of 101-29-1, the publication is Acta Horticulturae (2010), 365-375, database is CAplus.

There has been an increase in popularity of grafting technique on muskmelon in agricultural production because grafting of melon increased its disease resistance to fusarium wilt, but melon’s (Cucumis melo L.) quality has been more serious inferior than its own-rooted melon. The volatiles substance plays an important role in melon fruit quality. We have found very little reports in literature for melon grafting varieties and using solid-phase microextraction (SPME). The objective of this experiment was to identify volatile and semivolatile compounds in two melon cultivars ‘Lu135’ and ‘Lu7475’, using solid-phase microextraction (SPME) with gas chromatog.-mass spectrometry (GC-MS). Fully ripe melon was squeezed through miracloth to produce rapid juice extracts for immediate headspace SPME GC-MS. One hundred forty two volatile compounds were separated in ripe muskmelon, they consisted of 56 esters, 27 alcs., 3 aldehydes, 17 ketones, 21 alkenes and 18 other substances. Among these compounds, types of esters and alcs. were the important aroma components accounting for over 74.75-93.46% of total peak area. The most abundant compounds in two cultivars were acetic acid, phenylmethyl ester (21.65-36.43%), acetic acid, hexyl ester (6.05-12.95%), Et acetate (2.89-9.94%), 1-butanol, 2-methyl-, acetate (5.84-7.82%). The total aromatic compounds and characteristic aromatic esters contents decreased in grafted melons than the own-rooted melon. The delightful fruit aroma in grafting melon was lower and thinner in comparison to own-rooted. Meanwhile, the aroma components of melon were altered because of grafting in adopting of melon. However, the effect of grafting on aroma components was different between two varieties. The total esters content and category in ‘Lu135’ was obviously lower in grafting melons than own-rooted and it had little chance on ‘Lu7475’.

Acta Horticulturae published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C5H10N2OS, Application In Synthesis of 101-29-1.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Yuanfei published the artcileCarboxylic Acids as Traceless Directing Groups for the Rhodium(III)-Catalyzed Decarboxylative C-H Arylation of Thiophenes, Computed Properties of 145343-76-6, the publication is Angewandte Chemie, International Edition (2015), 54(12), 3817-3821, database is CAplus and MEDLINE.

A rhodium(III)-catalyzed carboxylic acid directed decarboxylative C-H/C-H cross-coupling of carboxylic acids with thiophenes was developed. With a slight adjustment of the reaction conditions based on the nature of the substrates, arylcarboxylic acids with a variety of substituents served as suitable coupling partners, and a broad variety of functional groups were tolerated. The method provided straightforward access to biaryl scaffolds with diverse substitution patterns, many of which have conventionally been synthesized through lengthy synthetic sequences. An illustrative example was the one-step gram-scale synthesis of biol. active I from 2-(4-methoxyphenyl)thiophene and 2-methoxy-4-methylbenzoic acid.

Angewandte Chemie, International Edition published new progress about 145343-76-6. 145343-76-6 belongs to iodides-buliding-blocks, auxiliary class Chloride,Iodide,Carboxylic acid,Benzene, name is 2-Chloro-4-iodobenzoic acid, and the molecular formula is C9H9F5Si, Computed Properties of 145343-76-6.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Xu, Niansheng published the artcileHelical polycycle molecular semiconductor for durable and efficient perovskite solar cells, Product Details of C6H13I, the publication is ACS Materials Letters (2022), 4(1), 11-20, database is CAplus.

Despite the efficiency comparable to crystalline silicon photovoltaics, it is still a severe concern on the long-term stability under the stress of heat, light, and bias potential for perovskite solar cell (PSC). Here, we report a triple aza[6]helicene-based mol. semiconductor (TBTA[6]H) characteristic of a fully fused conjugated backbone. TBTA[6]H presents superior solubility and glass-transition temperature (T_g). An air-doped composite of TBTA[6]H with a high elec. conductivity of 353μS cm^-1 is still featured by a T_g of 112°C, enabling the fabrication of 22% efficiency, 85°C durable PSCs. The TBTA[6]H composite not only exhibits an excellent morphol. stability at 85°C in PSCs, but also remarkably attenuates the thermal degradation of photoactive perovskite layer. The cell with TBTA[6]H also displays an excellent operation stability under the continuous full sunlight soaking at 55°C.

ACS Materials Letters published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C7H3ClN2O3, Product Details of C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Fang, Lingyi published the artcileA triple helicene based molecular semiconductor characteristic of a fully fused conjugated backbone for perovskite solar cells, Formula: C6H13I, the publication is Energy & Environmental Science (2022), 15(4), 1630-1637, database is CAplus.

We herein report a triple helicene based mol. semiconductor (TBPC-611), characteristic of a fully fused conjugated backbone containing multiple pyrrole rings. TBPC-611 can be solution-processed with nonvolatile 4-tert-butylpyridinium bis(trifluoromethanesulfonyl)imide into a morphol. heat-resistant composite thin film which also possesses high elec. conductivity and high hole mobility. These combined quality factors allow for its use as the protective hole-transport layer of PSCs with 22.1%-efficiency which are remarkably stable at 85°C for 2000 h. Joint exptl. and theor. investigations have uncovered the crucial correlation of the permeation of internal and external gaseous mols. with the thermal decomposition of perovskites, shedding light on durable perovskite optoelectronic devices.

Energy & Environmental Science published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Formula: C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Yang, Chengbin published the artcileDiscovery of a Novel Series of 7-Azaindole Scaffold Derivatives as PI3K Inhibitors with Potent Activity, SDS of cas: 757978-19-1, the publication is ACS Medicinal Chemistry Letters (2017), 8(8), 875-880, database is CAplus and MEDLINE.

The phosphoinositide 3-kinase (PI3K) inhibitors potently inhibit the signaling pathway of PI3K/AKT/mTOR, which provides a promising new approach for the molecularly targeted cancer therapy. In this work, a novel series of 7-azaindole scaffold derivatives was discovered by the fragment-based growing strategy. The structure-activity relationship profiles identified that the 7-azaindole scaffold derivatives exhibit potent activity against PI3K at mol. and cellular levels as well as cell proliferation in a panel of human tumor cells.

ACS Medicinal Chemistry Letters published new progress about 757978-19-1. 757978-19-1 belongs to iodides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Bromide,Iodide,Sulfamide,Benzene, name is 5-Bromo-3-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine, and the molecular formula is C10H9ClN2O, SDS of cas: 757978-19-1.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wang, Long published the artcileHigh-Lying 3¹Ag Dark-State-Mediated Singlet Fission, Recommanded Product: 1-Iodohexane, the publication is Journal of the American Chemical Society (2021), 143(15), 5691-5697, database is CAplus and MEDLINE.

Singlet fission (SF), the conversion of one high-energy singlet to two low-energy triplets, provides the potential to increase the efficiency of photovoltaic devices. In the SF chromophores with C_2h symmetry, exemplified by polyenes, singlet-to-triplet conversion generally involves a low-lying 2¹A_g dark state, which serves as either a multiexciton (ME) intermediate to promote the SF process or a parasitic trap state to shunt excited-state populations via internal conversion. This controversial behavior calls for a deep understanding of dark-state-related photophysics involving the higher-lying singlet state. However, the optical “dark” and “transient” nature of these dark states and strong correlation feature of double exciton species make their characterization and interpretation challenging from both exptl. and computational perspectives. In the present work combining transient spectroscopy and multireference electronic structure calculations (XDW-CASPT2), we addressed a new photophys. model, i.e., a high-lying 3¹Ag dark-state-mediated ultrafast SF process in the benzodipyrrolidone (BDPP) skeleton. Such a 3¹Ag dark state with distinctive double excitation character, described as the ME state, could be populated from the initial 1¹Bu bright state on an ultrafast time scale given the quasi-degeneracy and intersection of the two electronic states. Furthermore, the suitable optical band gap and triplet energy, high triplet yield, and excellent photostability render BDPP a promising SF candidate for photovoltaic devices. These results not only enrich the arsenal of SF materials but also shed new insights into the understanding of dark-state-related photophysics, which could promote the development of new SF-active materials.

Journal of the American Chemical Society published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C7H13NO2, Recommanded Product: 1-Iodohexane.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Li, Ling published the artcilePreparation and Application of α-Imino Ketones through One-Pot Tandem Reactions Based on Heyns Rearrangement, Quality Control of 53279-83-7, the publication is Organic Letters (2021), 23(17), 6819-6824, database is CAplus and MEDLINE.

A metal-free and operationally simple strategy was developed to generate α-imino ketones with high regioselectivity. Meanwhile, the method allowed for the preparation of various N,O-ketals with high regioselectivities and diastereoselectivities through cascade reactions in one pot.

Organic Letters published new progress about 53279-83-7. 53279-83-7 belongs to iodides-buliding-blocks, auxiliary class Iodide,Amine,Benzene,Alcohol, name is (2-Amino-5-iodophenyl)methanol, and the molecular formula is C7H8INO, Quality Control of 53279-83-7.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Yang, Eunkyung published the artcileIntegration of Cyanine, Merocyanine and Styryl Dye Motifs with Synthetic Bacteriochlorins, Application In Synthesis of 606-55-3, the publication is Photochemistry and Photobiology (2016), 92(1), 111-125, database is CAplus and MEDLINE.

Understanding the effects of substituents on spectral properties is essential for the rational design of tailored bacteriochlorins for light-harvesting and other applications. Toward this goal, three new bacteriochlorins containing previously unexplored conjugating substituents have been prepared and characterized. The conjugating substituents include two pos. charged species, 2-(N-Et 2-quinolinium)vinyl- (B-1) and 2-(N-Et 4-pyridinium)vinyl- (B-2), and a neutral group, acroleinyl- (B-3); the charged species resemble cyanine (or styryl) dye motifs whereas the neutral unit resembles a merocyanine dye motif. The three bacteriochlorins are examined by static and time-resolved absorption and emission spectroscopy and d. functional theor. calculations B-1 and B-2 have Q_y absorption bathochromically shifted well into the NIR region (822 and 852 nm), farther than B-3 (793 nm) and other 3,13-disubstituted bacteriochlorins studied previously. B-1 and B-2 have broad Q_y absorption and fluorescence features with large peak separation (Stokes shift), low fluorescence yields, and shortened S₁ (Q_y) excited-state lifetimes (∼700 ps and ∼100 ps). More typical spectra and S₁ lifetime (∼2.3 ns) are found for B-3. The combined photophys. and mol.-orbital characteristics suggest the altered spectra and enhanced nonradiative S₁ decay of B-1 and B-2 derive from excited-state configurations in which electron d. is shifted between the macrocycle and the substituents.

Photochemistry and Photobiology published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C10H15ClO3S, Application In Synthesis of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Song, Di published the artcileAcridinium-conjugated aromatic heterocycles as highly potent FtsZ inhibitors: Design, synthesis, and biological evaluation, Application In Synthesis of 638-45-9, the publication is Archiv der Pharmazie (Weinheim, Germany) (2022), 355(6), 2100400, database is CAplus and MEDLINE.

The epidemic of multidrug resistance (MDR) is a serious threat to public health, and new classes of antibiotics with novel mechanisms of action are in critical need. We rationally designed and efficiently synthesized three series of new chem. entities with potential antibacterial activity targeting filamenting temperature-sensitive mutant Z (FtsZ). Evaluation of these compounds against a panel of Gram-pos. bacteria including MDR and vancomycin-resistant Enterococcus strains indicated that most compounds showed enhanced antibacterial efficacy, comparable or even superior to the reference drugs. The newly synthesized compounds proved to be substrates of the Escherichia coli efflux pump AcrB, thus affecting the activity. Their structure-activity relationships were summarized in detail. The most potent compound 10f quickly eliminated bacteria in a bactericidal mode, with low susceptibility to induce bacterial resistance. Further mechanistic studies with the BsFtsZ protein revealed that 10f functioned as an effective FtsZ inhibitor through altering the dynamics of FtsZ self-polymerization via a stimulatory mechanism, which leads to inhibition of cell division and cell death. Besides, 10f not only displayed no obvious cytotoxicity to mammalian cells but also had a high efficacy in a murine model of bacteremia in vivo. Regarded as a whole, our findings highlight 10f as a promising new FtsZ-targeting bactericidal agent.

Archiv der Pharmazie (Weinheim, Germany) published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C5H10O2S, Application In Synthesis of 638-45-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wang, Shan published the artcileEnantioselective access to chiral aliphatic amines and alcohols via Ni-catalyzed hydroalkylations, Quality Control of 638-45-9, the publication is Nature Communications (2021), 12(1), 2771, database is CAplus and MEDLINE.

A nickel-catalyzed enantioselective hydroalkylation of acyl enamines R¹C(O)N(R²)CH=CH₂ (R¹ = C₆H₅, 1-naphthyl, 2-furyl, etc.; R² = H, Me) and enol esters R³C(O)OCH=CH₂R⁴ (R³ = C₆H₅, 4-CH₃OC₆H₄, 2-naphthyl; R⁴ = H, C₄H₉, C₆H₁₃, (CH₂)₄Cl) with alkyl halides R⁵I [R⁵ = 2-phenylethyl, 3-(thiophen-2-yl)propyl, 3-(9H-carbazol-9-yl)propyl, etc.] to afford enantioenriched α-branched aliphatic acyl amines (R)-R¹C(O)N(R²)CH(R⁵)Me and esters R³C(O)OCH(R⁵)CH₂R⁴ in good yields with excellent levels of enantioselectivity has been described. The operationally simple protocol provides a straightforward access to chiral secondary alkyl-substituted amine and secondary alkyl-substituted alc. derivatives from simple starting materials with great functional group tolerance.

Nature Communications published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C17H16O2, Quality Control of 638-45-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com