Month: December 2022

Mokhtar, Hassan M. published the artcileSynthesis of hydrazones with antituberculous activity, Application In Synthesis of 39115-95-2, the publication is Pharmazie (1979), 34(3), 150-2, database is CAplus.

The reactions of cinnamoylacetaldehyde, Et 2,4-dioxo-6-phenylhexenoate, and 2-carboethoxy-3-hydroxy-1,4-naphthoquinone with acyl- or arylhydrazines, substituted o-phenylenediamines, and ethanolamine are reported. The hydrazones are converted to the corresponding N-acyl- or N-arylpyrazole derivatives

Pharmazie published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Application In Synthesis of 39115-95-2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Mokhtar, Hassan M. published the artcileHydrazine and quinoxaline derivatives of aryl L-ascorbic acid analogs, Recommanded Product: 4-Iodobenzohydrazide, the publication is Pharmazie (1978), 33(11), 709-11, database is CAplus and MEDLINE.

Oxidation of the hydroxytetronimides I (R = p-ClC₆H₄, p-MeOC₆H₄, m-O₂NC₆H₄, 2-phenyl-4-triazolyl), prepared from RCHO, OCHCHO.2NaHSO₃, and KCN, with HNO₂ gave the butyrolactones II. II was treated with acyl- or arylhydrazones to give the bisacyl- or bisarylhydrazones. Reaction of II with o-H₂NC₆H₄NH₂ gave quinoxaline derivatives, e.g. III, or Schiff bases, e.g. IV, depending on the reactant ratio.

Pharmazie published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Recommanded Product: 4-Iodobenzohydrazide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Krasnova, M. A. published the artcileQuantitative analysis of iodine-containing pharmaceutical preparations by combustion in oxygen, Safety of 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, the publication is Farmatsiya (Moscow, Russian Federation) (1969), 18(3), 57-60, database is CAplus and MEDLINE.

Anal. of I-containing (50-69% of I) pharmaceutical preparations by combustion in O utilizes a new modification of the method and a comparison is made with the existing ones. The sample (0.02-0.03 g.) is placed on the Pt grid (initially not in contact with the solution), 10 ml. 2N KOH and 50 ml. H2O are poured into a flask and O bubbled through 5 min. Then the sample is burned (20-30 sec.) and the flask tightly stopped. The content is then shaken (5-6 min.) and allowed to stand for 10 min. more. Br (5 ml.) and AcOH are then added, the solution stirred and 0.3 ml. 85% HCO2H added. After the solution has lost its color, 20 ml. of N H2SO4 and 0.05 g. KI are added, and the flask allowed to stand in dark 5 min. The liberated I is titrated with 0.1N Na2S2O3 (1% starch indicator). The time of anal. is 30 min. The relative error is �.4%.

Farmatsiya (Moscow, Russian Federation) published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C7H5I2NO3, Safety of 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Kramer, Claus Ruediger published the artcileDistribution of arylcarboxylic acid hydrazides in the n-octanol-water system, Product Details of C7H7IN2O, the publication is Zeitschrift fuer Chemie (1978), 18(9), 348-9, database is CAplus.

Distribution coefficients (P) of RC₆H₄CONHNH₂ (I; R = H, p-Me, m-Me, m-NH₂, o-OH, m-Cl, etc.) were determined in the octanol-water system via UV spectral data; Hansch π-substituent constants were calculated from P. Linear correlations of log P for the p– and m– substituted I with π values for the corresponding RC₆H₄CONH₂ and RC₆H₄OCH₂CO₂H were given. An observed ortho effect in I was ascribed to intramol. H bonding.

Zeitschrift fuer Chemie published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Product Details of C7H7IN2O.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Klaeboe, Peter published the artcileThe Raman spectra of some iodine, bromine, and iodine monochloride charge-transfer coomplexes in solution, Related Products of iodides-buliding-blocks, the publication is Journal of the American Chemical Society (1967), 89(15), 3667-76, database is CAplus.

The Raman spectra of I2, Br2, and ICl have been studied in various solutions in the region below 400 cm.-1 by means of a Raman spectrophotometer equipped with a 50 mw. He-Ne laser. Quite satisfactory Raman spectra of these colored solutions were obtained, but for some Br and ICl complexes chem. reactions occurred. The observed Raman frequencies for the halogens or the interhalogen were considerably lower than the corresponding gas values, and the data have been interpreted on the basis of charge-transfer interaction. Some very strong donor-halogen interactions were observed, in which the stretching force constant of the halogens was reduced to approx. half the gas value. A Raman band at 163 cm.-1 in the pyridineiodine system was interpreted as the N-I stretching mode; otherwise no Raman bands were observed which can with certainty be assigned to the stretching of the donor-halogen charge-transfer bond. 36 references.

Journal of the American Chemical Society published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, Related Products of iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Ikemoto, Isao published the artcileStructure of molecular compounds, Application In Synthesis of 6443-90-9, the publication is Kagaku no Ryoiki (1969), 23(5), 502-12, database is CAplus.

The Mulliken theory for charge transfer interaction between an electron acceptor and electron donor is reviewed and the overlap and orientation principle in relation to the structure of complexes is explained. Structures of the following charge transfer complexes are discussed: fo r π-σ complexes, donor (C6H6), acceptor (Br2, I2, or Cl2); for n-σ complexes, donor (1,4-dioxane, Me2CO, 1,4-dithiane, 1,4-diselenane, hexamethyl-enetetramine, trimethylamine, pyridine, or γ-picoline), acceptor (Br2, ICl, Cl2, I2); for π-π complexes, acceptor (trinitrobenzene, p-benzoquinone, chloranil, pyromellitic acid anhydrous, tetracyanobenzene, tetracyanoethylene, tetramethyluric acid, TCNQ), donor (anthracene, azulene, indole, skatole, p-iodoaniline, triaminobenzene, phenol, hydroquinone, resorcinol, p-chlorophenol, bromophenol, hexamethylbenzene, perylene, naphthalene, pyrene, N,N,N’,N’-tetramethylphenylenediamine, N,N-dimethylphenylenediamine, 1,2,4,5-tetramethylbenzene, ferrocenen, 3,4-benzopyrene, bis(8-hydroxyquinolinato)copper(II)). For the π-π complexes, the crystallographic data were tabulated.

Kagaku no Ryoiki published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, Application In Synthesis of 6443-90-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Hofmann, Thomas published the artcileIdentification of Novel Colored Compounds Containing Pyrrole and Pyrrolinone Structures Formed by Maillard Reactions of Pentoses and Primary Amino Acids, Recommanded Product: Ethyl 2-Iodopropionate, the publication is Journal of Agricultural and Food Chemistry (1998), 46(10), 3902-3911, database is CAplus.

Heating of pentoses with alanine in a ratio of 10:1 in aqueous solution at pH 7.0 generated the yellow 2-[(2-furyl)methylidene]-4-hydroxy-5-methyl-2H-furan-3-one, being well in line with data reported in the literature. Decreasing the relative concentrations of the pentose produced further colored nitrogen-containing compounds, among which (S)-4-hydroxy-5-methyl-2-[N-(1′-carboxyethyl)pyrrolyl-2-methylidene]-2H-furan-3-one could be identified by spectroscopic and synthetic experiments On the other hand, thermal treatment of an aqueous solution of pentose and L-alanine in the presence of furan-2-carboxaldehyde led to the formation of the novel red (2R)-4-oxo-3,5-bis[(2-furyl)methylidene]tetrahydropyrrolo[1,2-c]-5(S)-(2-furyl)oxazolidine and its 5(R)-(2-furyl)oxazolidine diastereomer, which were characterized by several 1D- and 2D-NMR techniques, LC/MS, and UV-vis spectroscopy as well as by synthesis of the chromophoric substructure. In addition, the red compounds (S)-4-[(E)-1-formyl-2-(2-furyl)ethenyl]-5-(2-furyl)-2-[(E)-(2-furyl)methylidene]-2,3-dihydro-α-amino-3-oxo-1H-pyrrole-1-acetic acid and the corresponding 2-[(Z)-(2-furyl)methylidene] isomer were identified in this Maillard mixture Quant. studies on the formation of these colorants clearly demonstrates the key role of 3-deoxypentos-2-ulose as an intermediate. Reaction pathways leading to the colorants from pentoses and alanine are discussed.

Journal of Agricultural and Food Chemistry published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Recommanded Product: Ethyl 2-Iodopropionate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Hassel, Odd published the artcileWeak intermolecular bonds in solids, Name: Pyridine Iodochloride complex, the publication is Dansk Tidsskrift for Farmaci (1962), 41-54, database is CAplus and MEDLINE.

A brief review of studies on charge-transfer bonds in complex compounds between halides (electron acceptors) and mols. containing O, N, and S, or the π-electrons of aromatic hydrocarbons, as electron donors. Electron-d. projections are given for pyridine-2I₂, pyridine-ICl, 2 acetonitrile-Br₂, CHI₃-3-quinoline, CHI₃-3S₈; the complexes 1,4-dioxane-halogen, acetone-Br₂ (1:1), hexamethylenetetramine-2Br₂, halogen-benzene, SbI₃-3S₈, oxalyl chloride (or bromide)-1,4-dioxane, and CHI₃-dithiane are discussed. Charge-transfer bonds were also found in crystals of cyanuric halides and oxalyl bromide, where an electron donor and acceptor are present.

Dansk Tidsskrift for Farmaci published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, Name: Pyridine Iodochloride complex.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Hassel, O. published the artcileStructures of electron-transfer and related molecular complexes in the solid state, SDS of cas: 6443-90-9, the publication is Molecular Physics (1958), 241-6, database is CAplus.

Results obtained in recent years from x-ray investigations of solid addition compounds thought to be formed by electron transfer between mols. containing closed shells are discussed. (1) Addition compounds of ethers (or thioethers) and halogen (X): The arrangement O-X-X (or with S) as well as O-X-X-O (dioxane) is linear. In cases of combinations of 2 different halogens the stronger bond is linked to the donor atom, e.g. RO-I-Cl. This is corroborated by the altered bond distances. (2) Pyridine and ICl (1:1): The whole complex is definitely planar, the bond distances being 2.30 and 2.54 A. for N-I and I-Cl bonds, resp. (3) Hexamethylenetetramine and Br (1:2): Both N-Br-Br are linear, one N-Br and the three C-N bonds forming a nearly regular tetrahedron. Exactly the same configuration is established for Me₃N-XY. For X,Y = I the distances for I-I and N-I, resp., 2.85 and 2.27 A. are obtained; if X = I, Y = Cl, the values are 2.53 and 2.30 A. for I-Cl and N-I, resp. These results invalidate Hantsch’s concept of solid addition compounds of the type (R₃NX)⁺Y^–. The assumption that the direct reaction products obtained from amines and halogens may without risk be recrystallized from nonaqueous solvents is also fallacious. As regards the structure of charge-transfer complexes, the space group (C 2/m) is determined as the most likely one for C₆H₆.Br₂. The crystal is built of chains consisting of alternating C₆H₆ and Br₂ mols. with the Br atoms symmetrically located about the common major axis of 2 neighboring C₆H₆ rings. The Br-Br distance differs little from the one in the isolated mol. The distance Br → center of nearest ring amounts to 3.36 A. Crystal structures of addition compounds between ethers and mols. containing active H are also being studied. There exists a bond between O of Et₂O and C of CHCl₂Br, the O-H-C separation being 3.1 A. It is certain that the 1:1 compound of dioxane and H₂SO₄ is built of chains, alternating in the components, with both H atoms of the acid taking part in H-bonding with the O atoms of the ether. The O-H-O bond appears to be of normal length. The surprisingly short N-X distances indicate a bond not essentially weaker than ordinary covalent bonds, whereas the lengthening of the adjacent X-X distances in comparison to X₂ purports weakening. As both X atoms are linked to the O atoms of dioxane in the crystalline addition compounds, there is strong indication that the second X in 1:1 complexes, evidently present in liquid mixtures, is essentially not altered by bond formation between O and the first X. It is, therefore, suggested that the X, which is directly bound to the donor, forms a 10-electron system, whereas the second X retains its original octet. In this case a linear arrangement would be expected (viz. I₃^–), as is found. In regard to the probable structure of addition complexes in liquid mixtures it is believed that the amine-X₂ and ether-X₂ complexes exhibit the linear arrangement. The keto-halogen structures (1:1) in the solid state are predicted to be chains, each keto O being linked to 2 independent X atoms; in this case an angle of about 110° is to be expected between 2 linear O-X-X-O arrangements meeting in the keto O.

Molecular Physics published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, SDS of cas: 6443-90-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Haristos, Demetrius A. published the artcileKinetic study of the oxidation of ring monosubstituted aroylhydrazines by copper(II) chloride. Application of the Hammett equation, Formula: C7H7IN2O, the publication is Chimika Chronika (1983), 12(3), 129-35, database is CAplus.

The oxidation kinetics of RC₆H₄CONHNH₂ (I; R = halo, NO₂, MeO) by CuCl₂, to give RC₆H₄CO₂H, was examined at 25-60° and pH 4.40-5.60. The reaction is first-order each in I and CuCl₂; the second order rate constant is inversely proportional to the H⁺ concentration The reaction has ρ – 0.10 with the points for I (R = m – F and p – NO₂) deviating significantly from the LFER. The substituent effect is involved mainly in the ability of I to form complexes with CuCl₂; the substituted effect on the electron transfer rate is negligible.

Chimika Chronika published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Formula: C7H7IN2O.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com