Pelcman, Benjamin published the artcile3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1, Computed Properties of 141998-77-8, the publication is Bioorganic & Medicinal Chemistry Letters (2015), 25(15), 3024-3029, database is CAplus and MEDLINE.
Investigation of 1N-substituted pyrazole-3-carboxanilides as 15-lipoxygenase-1 (15-LOX-1) inhibitors demonstrated that the 1N-substituent was not essential for activity or selectivity. Addnl. halogen substituents on the pyrazole ring, however, increased activity. Further development led to triazole-4-carboxanilides and 2-(3-pyrazolyl) benzoxazoles, which are potent and selective 15-LOX-1 inhibitors.
Bioorganic & Medicinal Chemistry Letters published new progress about 141998-77-8. 141998-77-8 belongs to iodides-buliding-blocks, auxiliary class Pyrazole,Iodide,Ester,Pyrazole, name is Ethyl 5-iodo-1H-pyrazole-3-carboxylate, and the molecular formula is C6H7IN2O2, Computed Properties of 141998-77-8.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com