McDermott, Todd S. published the artcileProcess research and initial scale-up of ABT-839: A farnesyl-transferase inhibitor, Name: Dimethyl 2-iodoterephthalate, the publication is ACS Symposium Series (2004), 59-69, database is CAplus.
The antitumor compound ABT-839 was synthesized in eight steps from com. available starting materials. The synthesis was carried out with a single purification prior to final salt isolation. The key sequence is an efficient bromination and a novel bis-coupling strategy that transforms the bi-aryl core to the penultimate ester in a single operation with no isolation in 94% yield. After bisulfate salt formation, the product was isolated as a crystalline solid. The synthesis was carried out on kilogram scale and gave an overall yield of 43%.
ACS Symposium Series published new progress about 165534-79-2. 165534-79-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Benzene,Ester, name is Dimethyl 2-iodoterephthalate, and the molecular formula is C10H9IO4, Name: Dimethyl 2-iodoterephthalate.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com