Billion, H.’s team published research in Klinische Wochenschrift in 33 | CAS: 101-29-1

Klinische Wochenschrift published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C7H5I2NO3, Application of 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid.

Billion, H. published the artcileThe distribution of radioactive Perabrodil M in humans and its application in renal clearance, Application of 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, the publication is Klinische Wochenschrift (1955), 1089-93, database is CAplus.

Human subjects were treated intravenously with 200-2250 mg. of Perabrodil M (I) labeled with radioactive iodine. Serum and urine radioactivity was determined for 180 min. as a measure of the I concentration Excretion of I in the urine paralleled the decline in serum I concentration At dose levels of 200-400 mg. and 2250 mg. the urinary excretion of I was 79.1 and 94.1%, resp., in 3 hrs., with half-time values of 44.5 and 32 min., resp. Renal clearance values obtained by slow infusion of I compared favorably with those obtained using p-aminohippuric acid.

Klinische Wochenschrift published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C7H5I2NO3, Application of 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com