Andrade, Carolina Horta published the artcileThree-dimensional quantitative structure-activity relationships for a large series of potent antitubercular agents, Name: 4-Iodobenzohydrazide, the publication is Letters in Drug Design & Discovery (2008), 5(6), 377-387, database is CAplus.
Comparative mol. field anal. (CoMFA) studies were conducted on a series of 100 isoniazid derivatives as anti-tuberculosis agents using two receptor-independent structural data set alignment strategies: (1) rigid-body fit, and (2) pharmacophore-based. Significant cross-validated correlation coefficients were obtained (CoMFA(1), q2 = 0,75 and CoMFA(2), q2 = 0.74), indicating the potential of the models for untested compounds The models were then used to predict the inhibitory potency of 20 test set compounds that were not included in the training set, and the predicted values were in good agreement with the exptl. results.
Letters in Drug Design & Discovery published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Name: 4-Iodobenzohydrazide.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com