Andrade, Carolina H. published the artcileFragment-based and classical quantitative structure-activity relationships for a series of hydrazides as antituberculosis agents, Recommanded Product: 4-Iodobenzohydrazide, the publication is Molecular Diversity (2008), 12(1), 47-59, database is CAplus and MEDLINE.
Worldwide, tuberculosis (TB) is the leading cause of death among curable infectious diseases. Multidrug-resistant Mycobacterium tuberculosis is an emerging problem of great importance to public health, and there is an urgent need for new anti-TB drugs. In the present work, classical 2D quant. structure-activity relationships (QSAR) and hologram QSAR (HQSAR) studies were performed on a training set of 91 isoniazid derivatives Significant statistical models (classical QSAR, q 2 = 0.68 and r 2 = 0.72; HQSAR, q 2 = 0.63 and r 2 = 0.86) were obtained, indicating their consistency for untested compounds The models were then used to evaluate an external test set containing 24 compounds which were not included in the training set, and the predicted values were in good agreement with the exptl. results (HQSAR,; classical QSAR).
Molecular Diversity published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Recommanded Product: 4-Iodobenzohydrazide.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com