Bioscience, Biotechnology, and Biochemistry published new progress about 161370-66-7. 161370-66-7 belongs to iodides-buliding-blocks, auxiliary class Chiral,Iodide,Amine,Aliphatic hydrocarbon chain,Ester,Amide, name is (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, and the molecular formula is C13H24INO4, Safety of (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate.
Amino, Yusuke published the artcileSynthesis and evaluation of L-cystathionine as a standard for amino acid analysis, Safety of (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, the publication is Bioscience, Biotechnology, and Biochemistry (2017), 81(1), 95-101, database is CAplus and MEDLINE.
L-Cystathionine is a key nonprotein amino acid related to metabolic conditions. The quant. determination of L-cystathionine in physiol. fluids by amino acid anal. is important for clin. diagnosis; however, certified reference material for L-cystathionine with satisfactory purity, content, and quantity has been unavailable until recently. Consequently, a practical and simple method for the preparation of L-cystathionine was examined, which involves thioalkylation of N-tert-butoxycarbonyl-L-cysteine tert-Bu ester, derived from L-cystine, with (2S)-2-(tert-butoxycarbonyl)amino-4-iodobutanoic acid tert-Bu ester, derived from L-aspartic acid, to obtain L-cystathionine with protecting groups, followed by single-step deprotection under mild conditions. This method produces L-cystathionine in high purity (99.4%) and having sufficient percentage content according to amino acid anal., which could be used as a standard for the amino acid anal. of physiol. fluids.
Bioscience, Biotechnology, and Biochemistry published new progress about 161370-66-7. 161370-66-7 belongs to iodides-buliding-blocks, auxiliary class Chiral,Iodide,Amine,Aliphatic hydrocarbon chain,Ester,Amide, name is (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, and the molecular formula is C13H24INO4, Safety of (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com