Zhang, Linfeng published the artcileMicrowave-Assisted Nickel-Catalyzed Rapid Reductive Coupling of Ethyl 3-iodopropionate to Adipic Acid, Recommanded Product: 1-Iodohexane, the publication is Catalysis Letters (2021), 151(8), 2339-2345, database is CAplus.
3-Iodopropionic acid (3-IPA) can be efficiently synthesized from the glycerol derivative glyceric acid (GA), which is a potential biomaterial-based platform mol. In this report, Et 3-iodopropionate was rapidly dimerized to di-Et adipate in a microwave reactor using NiCl2.6H2O as a catalyst, co-catalyzed by Mn and the 1, 10-Phenanthroline monohydrate ligand. Under the optimum reaction conditions, di-Et adipate can be obtained with 84% yield at 90°C in just 5 min. Di-Et adipate was hydrolyzed to obtain the adipic acid (AA) in 89% yield with an acid catalyst. AA is an important chem. and a monomer for producing a wide range of high-performance polymeric substances. This rapid coupling method is also applicable to other alkyl halides.
Catalysis Letters published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C18H12ClNO, Recommanded Product: 1-Iodohexane.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com