Spanik, Ivan published the artcileGC separation of 2-substituted ethyl propionate enantiomers on permethylated and 2,6-dimethyl-3-pentyl β- and γ-cyclodextrin stationary phases, COA of Formula: C5H9IO2, the publication is Journal of Separation Science (2005), 28(12), 1347-1356, database is CAplus and MEDLINE.
The capillary gas chromatog. enantiomer separation of eight congeneric compounds CH3-HCX-COOC2H5 (X = Cl, Br, I, CN, OH, OC2H5, OC6H5 and NHCOCF3) on four different permethyl- and 2,6-di-O-methyl-3-O-pentyl- β- and γ-CD stationary phases was studied. The separation of enantiomers was evaluated in terms of the interactions of the X substituent of studied derivatives, as well as the nature of the 3-O-alkyl group in the 2,6-di-O-methyl-3-O-alkyl-CDs and the CDs cavity size. The differences in thermodn. data [ΔH and -ΔS] obtained for studied compounds and the selectivity of modified β- and γ-cyclodextrin phases in gas chromatog. separation were evaluated. ΔH values were compared with a ΔH value of an achiral standard (Et propionate, where X = H) to obtain the contribution of a particular substituent to the overall interaction energy. The variation in the enantiomeric separation with temperature and the retention order of these compounds on a given cyclodextrin capillary column depends on the nature of the substituents bonded to stereogenic carbon atom. The temperature dependencies of selectivity factors, In α on 1/T, were both linear as well as nonlinear, inter alia depending on the number of glucopyranose units of the CD derivatives The enantiospecific thermodn. data [Δ21(ΔH)] and [-Δ21(ΔS)] which characterize the chiral recognition in the separation system were used to gain more insight into the mechanistic aspects of the enantioseparations on permethylated and 2,6-di-O-methyl-3-O-pentyl-β- and γ-cyclodextrins.
Journal of Separation Science published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C15H14O3, COA of Formula: C5H9IO2.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com