Siebum, Arjan H. G.’s team published research in European Journal of Organic Chemistry in | CAS: 161370-66-7

Siebum, Arjan H. G. published the artcileAccess to any site-directed isotopomer of methionine, selenomethionine, cysteine, and selenocysteine – use of simple, efficient modular synthetic reaction schemes for isotope incorporation, Quality Control of 161370-66-7, the publication is European Journal of Organic Chemistry (2004), 2905-2913, database is CAplus.

Simple modular reaction schemes that allow access to any isotopomer of protected serine and homoserine have been worked out. These systems could be simply converted into cysteine, selenocysteine, homocysteine, homoselenocysteine, the essential amino acid methionine, and selenomethionine by Mitsunobu chem. These sulfur- and selenium-containing amino acids fulfil many essential roles in the living organism. In addition, homoserine could be converted in a few steps into optically active L-vinylglycine. As well as the stable isotopes ¹³C, ¹⁵N, ¹⁷O, and ¹⁸O, the radioactive isotopes of sulfur, selenium and carbon can also be easily introduced in a site-directed fashion. In view of the wide scope of the Mitsunobu reaction, we feel that many more important systems with the carbon skeleton of serine and homoserine should be preparable through this basic chem. in any site-directed isotopically labeled form.

European Journal of Organic Chemistry published new progress about 161370-66-7. 161370-66-7 belongs to iodides-buliding-blocks, auxiliary class Chiral,Iodide,Amine,Aliphatic hydrocarbon chain,Ester,Amide, name is (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, and the molecular formula is C8H9NOS, Quality Control of 161370-66-7.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com