Tanner, George A. published the artcileReabsorption and secretion of p-aminohippurate and Diodrast in Necturus kidney, HPLC of Formula: 101-29-1, the publication is American Journal of Physiology (1966), 210(2), 221-31, database is CAplus and MEDLINE.
Intact animals spontaneously show net reabsorption, no net transport, or net secretion of p-aminohippurate(PAH) and Diodrast. Net reabsorption was converted to net secretion by intraarterial doses of fatty acids such as octanoate. In kidneys perfused with modified Ringer solution, strong net PAH reabsorption was observed; with 1mM octanoate, net secretion was usually produced. The action of octanoate is specific and reversible. With PAH-carboxyl-14C perfused from either the aortic or renal portal side and unlabeled PAH from the opposite side, urine PAH sp. activity differed from that of filtered PAH. Unidirectional PAH movements, calculated using a 2-compartment analysis, suggest that Diodrast inhibits reabsorptive and secretory movements, whereas octanoate inhibits primarily the reabsorptive movement. Tubular transport of PAH and Diodrast in Necturus kidney may involve active processes which move these compounds into proximal tubule cells from luminal and peritubular sides.
American Journal of Physiology published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C8H7NO4, HPLC of Formula: 101-29-1.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com