Liu, Wei-wei published the artcileSynthesis, characterization, and biological evaluation of some novel glycosyl 1,3,4-thiadiazole derivatives as acetylcholinesterase inhibitors, Formula: C7H7IN2O, the publication is Heterocycles (2015), 91(2), 275-286, database is CAplus.
The corresponding 4-substituted glycosyl thiosemicarbazide derivatives were obtained by the reaction of glycosyl isothiocyanate with various hydrazides. Further cyclization with the system of p-TsCl/TEA led to the formation of N-glycosyl-5-substituted 1,3,4-thiadiazole-2-amine. Subsequent removal of the acetyl groups were conducted using the system of NaOMe/MeOH. The chem. structures of all new products were confirmed by IR, 1H NMR and ESI-HRMS. The acetylcholinesterase (AChE) inhibitory activities of those compounds were tested by Ellman’s method. Among them, the compound I possessed the best acetylcholinesterase-inhibition activity with IC50 of 18.38 ± 0.89 μM.
Heterocycles published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Formula: C7H7IN2O.
Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com