Regiospecific N-Arylation of Aliphatic Amines under Mild and Metal-Free Reaction Conditions was written by Purkait, Nibadita;Kervefors, Gabriella;Linde, Erika;Olofsson, Berit. And the article was included in Angewandte Chemie, International Edition in 2018.Safety of Bis(2,4,6-trimethylphenyl)iodonium triflate The following contents are mentioned in the article:
A transition metal-free N-arylation of primary and secondary amines with diaryliodonium salts is presented. Both acyclic and cyclic amines are well tolerated, providing a large set of N-alkyl anilines. The methodol. is unprecedented among metal-free methods in terms of amine scope, the ability to transfer both electron-withdrawing and electron-donating aryl groups, and efficient use of resources, as excess substrate or reagents are not required. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Safety of Bis(2,4,6-trimethylphenyl)iodonium triflate).
Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Safety of Bis(2,4,6-trimethylphenyl)iodonium triflate
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com