Catalytic Atropenantioselective Heteroannulation between Isocyanoacetates and Alkynyl Ketones: Synthesis of Enantioenriched Axially Chiral 3-Arylpyrroles was written by Zheng, Sheng-Cai;Wang, Qian;Zhu, Jieping. And the article was included in Angewandte Chemie, International Edition in 2019.Application of 676267-05-3 The following contents are mentioned in the article:
In the presence of Ag2O and a quinine- or quinidine-derived phosphine, arylethynyl aryl ketones such as I (R = Ph, 4-BrC6H4, 4-ClC6H4, 4-MeOC6H4, 4-MeC6H4, 4-t-BuC6H4, 3-MeOC6H4; R1 = Me, Et, i-Pr, Ac) underwent enantioselective cycloaddition reactions with isocyanoacetates such as Et isocyanoacetate to yield (aryl)aroylpyrrolecarboxylates such as II (R = Ph, 4-BrC6H4, 4-ClC6H4, 4-MeOC6H4, 4-MeC6H4, 4-t-BuC6H4, 3-MeOC6H4; R1 = Me, Et, i-Pr, Ac) in 46-98% yields and in 82-96% ee. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Application of 676267-05-3).
2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Application of 676267-05-3
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com