Synthesis of [18F]fluoroarenes from the reaction of cyclotron-produced [18F]fluoride ion with diaryliodonium salts was written by Shah, Aneela;Pike, Victor W.;Widdowson, David A.. And the article was included in Journal of the Chemical Society in 1998.Recommanded Product: 139139-80-3 The following contents are mentioned in the article:
Diaryliodonium salts have been shown to react with fluoride ion at 80° in acetonitrile to generate aryl fluorides. The regioselectivity is controlled electronically and by the bulk of the ortho-substituents on the rings, with the latter the dominant factor such that electron-rich rings can be fluorinated. Ortho-substituted aryl fluorides can be selectively produced from unsym. diaryliodonium salts. The process has been used to synthesize [18F] labeled aromatics using cyclotron generated [18F]fluoride ion. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Recommanded Product: 139139-80-3).
Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Recommanded Product: 139139-80-3
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com