QSAR of nitro-diphenylethers as inhibitors of cyclic photophosphorylation was written by Oettmeier, Walter;Masson, Klaus;Donner, Andreas. And the article was included in Zeitschrift fuer Naturforschung in 1988.Quality Control of 1-Iodo-4-(4-nitrophenoxy)benzene The following contents are mentioned in the article:
Twenty-five nitro-diphenylethers were synthesized and assayed for their inhibitory activity in N-methylphenazonium-methosulfate-mediated cyclic photophosphorylation. Their pI50-values ranged 3.5-5.3. A QSAR-anal. revealed that the lipophilicity of the nitro-diphenylethers as expressed by ∑π played a major role. In addition, the Taft steric parameter Es in positions 6′, 4′ and 2′ (in decreasing order) contributed to the inhibitory activity. For maximal biol. activity, positions 4′ and 6′ should be left unsubstituted, whereas a bulky substituent is required for position 2′. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Quality Control of 1-Iodo-4-(4-nitrophenoxy)benzene).
1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Quality Control of 1-Iodo-4-(4-nitrophenoxy)benzene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com