Base promoted direct C4-arylation of 4-substituted-pyrazolin-5-ones with diaryliodonium salts was written by Mao, Song;Geng, Xu;Yang, Yang;Qian, Xiaofei;Wu, Shengying;Han, Jianwei;Wang, Limin. And the article was included in RSC Advances in 2015.Formula: C17H18F3IO3S The following contents are mentioned in the article:
A metal-free approach for the C4-arylation of 4-substituted-pyrazolin-5-ones I (R = H, H2CHC:CH2, H2CC6H5, 4-F-C6H4CH2, etc.; R1 = CH3, C6H5; R2 = C6H5, 4-H3CC6H4, 4-F3CC6H4) with diaryliodonium salts was developed. The reaction proceeded smoothly at room temperature in the presence of DMAP (4-dimethylaminopyridine). As a result, a wide range of desired multi-substituted pyrazolin-5-one derivatives II were obtained in good to excellent yields (20-98%). This study involved multiple reactions and reactants, such as Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4Formula: C17H18F3IO3S).
Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4) belongs to iodide derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Formula: C17H18F3IO3S
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com