Diarylation of N- and O-nucleophiles through a metal-free cascade reaction was written by Linde, Erika;Bulfield, David;Kervefors, Gabriella;Purkait, Nibadita;Olofsson, Berit. And the article was included in Chem in 2022.Formula: C19H22F3IO3S The following contents are mentioned in the article:
Nucleophilic aromatic substitution is a classical tool for arylation of heteroatom nucleophiles, and recent developments in hypervalent iodine-mediated arylations allow a wide scope of substrates. The benefits of these strategies were combined to enable an efficient and transition-metal-free difunctionalization of N- and O-nucleophiles with two structurally different aryl groups and to provide di- and triarylamines and diaryl ethers in one single step (>100 examples). The core of this strategy is the unique reactivity discovered with specifically designed fluorinated diaryliodonium salts, which unveils novel reaction pathways in hypervalent iodine chem. The methodol. is suitable for diarylation of aliphatic amines, anilines, ammonia and even water. It tolerates a wide variety of functional and protecting groups, with the retained iodine substituent easily accessible for derivatization of the products. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).
Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Formula: C19H22F3IO3S
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com