Efficient and Divergent Synthesis of Medium-Sized Lactams through Zinc-Catalyzed Oxidative Cyclization of Indolyl Ynamides was written by Li, Hang-Hao;Ye, Si-Han;Chen, Yang-Bo;Luo, Wen-Feng;Qian, Peng-Cheng;Ye, Long-Wu. And the article was included in Chinese Journal of Chemistry in 2020.HPLC of Formula: 349404-93-9 The following contents are mentioned in the article:
An efficient zinc-catalyzed oxidative cyclization of readily available indolyl ynamides has been developed, enabling rapid and practical access to a diverse array of valuable medium-sized lactams I (R1 = H, 10-Me, 10-Cl, etc.; R2 = Ph, 4-MeC6H4, 3-MeOC6H4, etc.; PG = Ms, Ts, Bs), II (R1 = H, 8-Me, 9-Br, etc.; R2 = Ph, 4-NCC6H4, 3-ClC6H4, etc.; PG = Ms, Ts, Bs) in mostly good to excellent yields with wide substrate scope. In addition, such an asym. synthesis has also been explored by employing the chiral substrate. This study involved multiple reactions and reactants, such as 4-Bromo-N-(2-iodophenyl)benzenesulfonamide (cas: 349404-93-9HPLC of Formula: 349404-93-9).
4-Bromo-N-(2-iodophenyl)benzenesulfonamide (cas: 349404-93-9) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.HPLC of Formula: 349404-93-9
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com