Transition-Metal-Free N-Arylation of Pyrazoles with Diaryliodonium Salts was written by Gonda, Zsombor;Novak, Zoltan. And the article was included in Chemistry – A European Journal in 2015.Recommanded Product: Mesityl(p-tolyl)iodonium trifluoromethanesulfonate The following contents are mentioned in the article:
A new synthetic method was developed for the N-arylation of pyrazoles using diaryliodonium salts. The transformation does not require any transition-metal catalyst and provides the desired N-(aryl)pyrazole derivatives rapidly under mild reaction condition in the presence of aqueous ammonia solution as a mild base without the use of inert atm. The chemoselectivity of unsym. diaryliodonium salts was also explored with large number of examples. The synthesis of the target compounds was achieved by a reaction of 3,5-diphenyl-1H-pyrazole with (phenyl)(2,4,6-trimethylphenyl)iodonium 1,1,1-trifluoromethanesulfonate, (6-chloro-3-pyridinyl)(4-methoxyphenyl)iodonium trifluoromethanesulfonate and related substances. The title compounds thus formed included 1,3,5-triphenyl-1H-pyrazole derivatives, 4-iodo-1,3,5-triphenyl-1H-pyrazole derivatives This study involved multiple reactions and reactants, such as Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4Recommanded Product: Mesityl(p-tolyl)iodonium trifluoromethanesulfonate).
Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4) belongs to iodide derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Recommanded Product: Mesityl(p-tolyl)iodonium trifluoromethanesulfonate
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com