Decomposition of the salts of p-X-benzenediazonium complexes by 18-crown-6 in p-iodoanisole was written by Eustathopoulos, Helene;Court, Jean;Lambeaux, Claude;Bonnier, Jane Marie. And the article was included in Nouveau Journal de Chimie in 1985.Safety of 1-Iodo-4-(4-nitrophenoxy)benzene The following contents are mentioned in the article:
The decomposition of para-substituted benzenediazonium ions complexed with 18-crown-6 has been studied. Anal. of the reaction products from the thermal decomposition of the complexed diazonium salts in p-iodoanisole solution showed that the nature of the para substituent drastically changed the reaction mechanism. The decomposition of the complex p-nitrobenzenediazonium ion proceeds through a radical pathway. In addition to isomeric (p-nitrophenyl)iodoanisoles, the decomposition affords 2,4′-dimethoxy-5-iodobiphenyl and 5,4′-dimethoxy-2-iodobiphenyl, which result from the attack of p-iodoanisole by p-anisidyl radicals derived from the 4-methoxy-4′-nitrophenyliodinyl radical. 4-Iodo-4′-nitrodiphenyl ether and 4-methoxy-4′-nitrobiphenyl could not be detected; therefore, with a strong electron-withdrawing substituent, the decomposition mechanism is exclusively homolytic. The thermal decomposition of the complexed p-chlorobenzenediazonium salt affords products derived from the reaction of the p-chlorophenyl cation and products derived from the reaction of the p-chlorophenyl radical. At [crown ether]/[p-ClC6H4N2+] = 6, the homolysis represents at least 30% of the total decomposition This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Safety of 1-Iodo-4-(4-nitrophenoxy)benzene).
1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Safety of 1-Iodo-4-(4-nitrophenoxy)benzene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com