Zoraghi, Roya published the artcileDiscovery of a 1,2-bis(3-indolyl)ethane that selectively inhibits the pyruvate kinase of methicillin-resistant Staphylococcus aureus over human isoforms, Name: 4-Iodo-3-nitrobenzonitrile, the publication is Bioorganic & Medicinal Chemistry Letters (2014), 24(21), 5059-5062, database is CAplus and MEDLINE.
Methicillin-resistant Staphylococcus aureus pyruvate kinase (MRSA PK) has recently been identified as a target for development of novel antibacterial agents. Testing a series of 1,2-bis(3-indolyl)ethanes against MRSA PK has led to the discovery of a potent inhibitor that is selective over human isoforms.
Bioorganic & Medicinal Chemistry Letters published new progress about 101420-79-5. 101420-79-5 belongs to iodides-buliding-blocks, auxiliary class Nitrile,Nitro Compound,Iodide,Benzene,Benzene Compounds, name is 4-Iodo-3-nitrobenzonitrile, and the molecular formula is C2H3N3, Name: 4-Iodo-3-nitrobenzonitrile.
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