Montgomery, Justin I.’s team published research in Journal of Medicinal Chemistry in 2012-02-23 | CAS: 884494-45-5

Journal of Medicinal Chemistry published new progress about Acinetobacter. 884494-45-5 belongs to class iodides-buliding-blocks, name is 2-Fluoro-4-iodo-6-methylpyridine, and the molecular formula is C6H5FIN, Formula: C6H5FIN.

Montgomery, Justin I. published the artcilePyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections, Formula: C6H5FIN, the main research area is pyridone methylsulfone hydroxamate LpxC inhibitor treatment gram neg infection.

The synthesis and biol. activity of a new series of LpxC inhibitors represented by pyridone methylsulfone hydroxamate 2a (I) is presented. Members of this series have improved solubility and free fraction when compared to compounds in the previously described biphenyl methylsulfone hydroxamate series, and they maintain superior Gram-neg. antibacterial activity to comparator agents.

Journal of Medicinal Chemistry published new progress about Acinetobacter. 884494-45-5 belongs to class iodides-buliding-blocks, name is 2-Fluoro-4-iodo-6-methylpyridine, and the molecular formula is C6H5FIN, Formula: C6H5FIN.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com