Tasch, Boris O. A. published the artcileOne-Pot Synthesis of Diazine-Bridged Bisindoles and Concise Synthesis of the Marine Alkaloid Hyrtinadine A, Recommanded Product: tert-Butyl 5-chloro-3-iodo-1H-indole-1-carboxylate, the main research area is diazine bridged bisindole preparation borylation Suzuki arylation iodoindole iodoazaindole; hyrtinadine A synthesis antitumor agent.
Diazine-bridged bisindoles are readily obtained from N-Boc-protected 3-iodoindoles and 3-iodo-7-azaindole in a pseudo three-component reaction involving a one-pot Masuda borylation-Suzuki arylation sequence. Some of the title compounds display promising cytotoxic properties. The versatility of this methodol. is illustrated by a very concise total synthesis of the marine alkaloid hyrtinadine A (I).
European Journal of Organic Chemistry published new progress about Antitumor agents. 1048039-49-1 belongs to class iodides-buliding-blocks, name is tert-Butyl 5-chloro-3-iodo-1H-indole-1-carboxylate, and the molecular formula is C13H13ClINO2, Recommanded Product: tert-Butyl 5-chloro-3-iodo-1H-indole-1-carboxylate.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com