Li, Yanyun published the artcileIron Catalyzed Asymmetric Hydrogenation of Ketones, Computed Properties of 63131-30-6, the main research area is ketone keto ester stereoselective hydrogenation iron chiral macrocyclic ligand; alc stereoselective preparation iron catalyzed.
Chiral mols., such as alcs., are vital for the manufacturing of fine chems., pharmaceuticals, agrochems., fragrances, and novel materials. These mols. need to be produced in high yield and high optical purity and preferentially catalytically. Among all the asym. catalytic reactions, asym. hydrogenation with H2 (AH) is the most widely used in the industry. With few exceptions, these AH processes use catalysts based on the three critical metals, rhodium, ruthenium, and iridium. Herein we describe a simple, industrially viable iron catalyst that allows for the AH of ketones, a process currently dominated by ruthenium and rhodium catalysts. By combining a chiral, 22-membered macrocyclic ligand with the cheap, readily available Fe3(CO)12, a wide variety of ketones have been hydrogenated under 50 bar H2 at 45-65°, affording highly valuable chiral alcs. with enantioselectivities approaching or surpassing those obtained with the noble metal catalysts. In contrast to AH by most noble metal catalysts, the iron-catalyzed hydrogenation appears to be heterogeneous.
Journal of the American Chemical Society published new progress about Enantioselective synthesis. 63131-30-6 belongs to class iodides-buliding-blocks, name is Ethyl 3-(4-iodophenyl)-3-oxopropanoate, and the molecular formula is C11H11IO3, Computed Properties of 63131-30-6.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com