Cheng, Dachen published the artcileSynthetic Entries to Substituted Bicyclic Pyridones, Product Details of C5H2F2IN, the main research area is bicyclic pyridone synthesis; Mitsunobu cyclodehydration bicyclic pyridone synthesis; Suzuki coupling bicyclic pyridone synthesis; imidazopyridinone pyridopyrimidinone pyridodiazepinone synthesis.
The synthesis of 6,6- and 5,6-bicyclic pyridone scaffolds (e.g. 2,3-dihydro-1-benzylimidazo[1,2-a]pyridin-5-one, 1,2,3,4-tetrahydro-6H-pyrido[1,2-a]pyrimidin-6-one and 1-benzyl-2,3,4,5-tetrahydropyrido[1,2-a][1,3]diazepin-7-one) was completed using (i) an intramol. Mitsunobu reaction and/or (ii) hydrolysis of a bicyclic pyridinium salt intermediate. Regioselective functionalization of the pyridone ring was achieved via either direct lithiation or use of the halogen dance reaction. Suzuki coupling then allows introduction of aryl units at C(7)/C(9) or C(8) onto the bicyclic pyridone scaffold at either an early or late stage in the synthetic sequence. Suzuki couplings involving iodopyridinium intermediates are particularly effective.
Organic Letters published new progress about Cyclocondensation reaction, intramolecular (Mitsunobu). 685517-67-3 belongs to class iodides-buliding-blocks, name is 2,6-Difluoro-3-iodopyridine, and the molecular formula is C5H2F2IN, Product Details of C5H2F2IN.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com