On September 14, 2017, Janetka, James W.; Mydock-McGrane, Laurel published a patent.Quality Control of 5-Bromo-2-iodobenzotrifluoride The title of the patent was Preparation of C-glycoside compounds useful for treating urinary tract infection. And the patent contained the following:
The present invention relates to mannosides I, wherein Ar is aryl, heteroaryl; Y1 and Y2 are independently H, hydroxyl, alkoxy, amino; were prepared and are useful as inhibitors of FimH and methods for the treatment or prevention of urinary tract infection, bacterial infection, Crohn’s disease, and inflammatory bowel disease. Thus, glycoside II was prepared and tested for its hemagglutination (EC>90 = 0.006 μM) inhibition and as FimH inhibitor. The experimental process involved the reaction of 5-Bromo-2-iodobenzotrifluoride(cas: 364-12-5).Quality Control of 5-Bromo-2-iodobenzotrifluoride
The Article related to antibacterial antagonist hemagglutination urinary tract infection glycoside preparation mannoside, alkyne azide cycloaddition suzuki coupling fimh inhibitor human antibiotic, triazole click preparation c glycoside urinary tract infection and other aspects.Quality Control of 5-Bromo-2-iodobenzotrifluoride
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com