Month: October 2022

Zhou, Yue; Zeng, Qingle; Zhang, Li published the artcile< Transition-metal-free synthesis of phenothiazines from S-2-acetamidophenyl ethanethioate and ortho-dihaloarenes>, Related Products of 2265-92-1, the main research area is acetamidophenyl ethanethioate dihaloarene cyclocondensation transition metal free; phenothiazine preparation.

An efficient cesium carbonate-mediated synthesis of phenothiazine derivatives from S-2-acetamidophenyl ethanethioates and ortho-dihaloarenes has been developed. This protocol affords an efficient approach for the construction of phenothiazine derivatives without the need of transition-metal catalyst or ligand. A plausible mechanism is proposed.

Synthetic Communications published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent) (ortho-dihalo). 2265-92-1 belongs to class iodides-buliding-blocks, and the molecular formula is C6H3F2I, Related Products of 2265-92-1.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wray, Victor; Lincoln, David N. published the artcile< The additivity of substituent effects upon J(FF) in polysubstituted fluorobenzenes: an update>, Quality Control of 2265-92-1, the main research area is fluorine spin coupling substituent effect.

Substituent constants nJFF values (n = 2-5) and calculated unperturbed couplings are reported for 1,2,3-, 1,2,4-, 1,3,2-, 1,3,4-, 1,3,5-, and 1,4,2-F2RC6H3 (R = NH2, OH, F, Cl, Br, I, CF3, CN, NO2). Substituent effects on 3JFF values are additive. A previous anal. (Abraham, R. J.; MacDonald, D. B.; Pepper, E. S., 1968) of 4JFF and 5JFF is updated.

Organic Magnetic Resonance published new progress about Aryl fluorides Role: PRP (Properties). 2265-92-1 belongs to class iodides-buliding-blocks, and the molecular formula is C6H3F2I, Quality Control of 2265-92-1.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chen, Yuhang; Zhang, Dingcheng; Sun, Mingze; Ding, Zhenhua published the artcile< Divergent synthesis of isoxazoles and 6H-1,2-oxazines via hypervalent iodine-mediated intramolecular oxygenation of alkenes>, Electric Literature of 1391728-13-4, the main research area is isoxazoles preparation; oxazine preparation; alkene intramol oxygenation hypervalent iodine mediated.

The divergent synthesis of isoxazoles I [R1 = Ph, 4-MeC6H4, 2-naphthyl, etc.; R2 = Ph, 2-naphthyl, 2-furyl, etc.] and 6H-1,2-oxazines II [R3 = Me, CH(Me)2, cyclohexyl, Bn; Ar = Ph, 4-FC6H4, 2-naphthyl, etc.] was realized using a hypervalent fluoroiodane reagent from β,γ-unsaturated oximes. The formation of a five- or six-membered ring is controlled by the substituents of the substrates combined with the reaction conditions. The reaction was performed under mild conditions and gave the products in moderate to good yields.

New Journal of Chemistry published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 1391728-13-4 belongs to class iodides-buliding-blocks, and the molecular formula is C9H10FIO, Electric Literature of 1391728-13-4.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Gao, Yuan; Sachinthani, K. A. Niradha; Zheng, Chao; Jarrett-Wilkins, Charlie; Johnston, Andrew; Sun, Meng-Jia; Najarian, Amin Morteza; Wang, Ya-Kun; Saidaminov, Makhsud I.; de Arquer, F. Pelayo Garcia; Seferos, Dwight S.; Hoogland, Sjoerd; Sargent, Edward H. published the artcile< Self-Aligned Non-Centrosymmetric Conjugated Molecules Enable Electro-Optic Perovskites>, Safety of 3-Fluoro-4-iodobenzonitrile, the main research area is self aligned non centrosym conjugated mol electro optic perovskite.

Solution-processed organic electro-optic (EO) chromophores are well suited for integration in optical modulators on silicon photonics chips. They contain highly conjugated mols. with polar functional groups offering large dipoles and a large nonlinear optical response. However, these mols. form centrosym. aggregates that hinder poling efficiency and the resultant macroscopic EO response. Furthermore, at elevated temperatures, the alignment of poled mols. can be lost, leading to a reduction in the EO response. Inorganic EO materials exhibit excellent thermal stability but lower performance. Here 2D metal halide perovskite scaffolds that align EO mols. are reported. The approach heralds a material design strategy that combines the features of organic and inorganic EO materials. The EO material exhibits promising thermal stability with a performance approaching that of organic EO materials. Anchor diammonium non-centrosym. mols. are anchored inside a 2D metal halide perovskite scaffold, thereby avoiding aggregation. The authors lever the thermal stability of this compound and pole the organic mols. under an elec. field at 533 K. The 2D perovskites exhibit a macroscopic EO coefficient of 68 pm V-1-a twofold increase over LiNbO3. D. functional theory calculations show that the in-plane alignment of the mol. dipole moments can account for the EO response.

Advanced Optical Materials published new progress about Density functional theory. 887266-99-1 belongs to class iodides-buliding-blocks, and the molecular formula is C7H3FIN, Safety of 3-Fluoro-4-iodobenzonitrile.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

You, Tingjie; Zeng, Si-Hao; Fan, Jianqiang; Wu, Liangliang; Kang, Fangyuan; Liu, Yungen; Che, Chi-Ming published the artcile< A soluble iron(II)-phthalocyanine-catalyzed intramolecular C(sp3)-H amination with alkyl azides>, SDS of cas: 2265-92-1, the main research area is pyrrolidine preparation; alkyl azide ditertbutyl dicarbonate amination iron catalyst.

Herein, a soluble iron(II)-phthalocyanine, [FeII(tBu4Pc)(py)2] (Pc = phthalocyaninato(2-)), as an effective catalyst in intramol. C(sp3)-H bond amination, with alkyl azides e.g., (4-azidobutyl)benzene as the nitrogen source, to afford the amination products e.g., I in moderate to excellent yields with a broad substrate scope was described.

Chemical Communications (Cambridge, United Kingdom) published new progress about Alkyl azides Role: RCT (Reactant), RACT (Reactant or Reagent). 2265-92-1 belongs to class iodides-buliding-blocks, and the molecular formula is C6H3F2I, SDS of cas: 2265-92-1.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Yang, Peng-Fei; Zhu, Lei; Liang, Jian-Xing; Zhao, Han-Tong; Zhang, Jian-Xin; Zeng, Xian-Wang; Ouyang, Qin; Shu, Wei published the artcile< Regio- and Enantioselective Hydroalkylations of Unactivated Olefins Enabled by Nickel Catalysis: Reaction Development and Mechanistic Insights>, SDS of cas: 167479-01-8, the main research area is mechanism hydroalkylation olefin alkyl halide regioselective enantioselective nickel catalyst; alkene alkyl halide nickel catalyst enantioselective regioselective hydroalkylation; alkyl amide preparation.

Direct construction of fully alkyl-substituted tertiary chiral centers remote to activating groups is highly challenging and desirable. Herein, a Ni-catalyzed enantioselective hydroalkylation of unactivated alkenes with unactivated alkyl halides at room temperature is reported, providing a general and practical access to fully alkyl-substituted tertiary stereogenic carbon centers not adjacent to activating groups. This reaction undergoes regio- and stereoselective hydrometalation of unactivated alkenes with a nontrivial Markovnikov selectivity, followed by cross-coupling with unactivated alkyl electrophiles to access trialkyl tertiary saturated stereogenic centers not adjacent to activating groups. The mild and robust conditions enable the use of terminal and internal unactivated alkenes and unactivated primary and secondary alkyl, benzyl and propargyl halides to construct diverse trialkyl tertiary stereogenic carbon centers with broad functional group tolerance. Moreover, exptl. investigations support the reaction undergoing irreversible and stereoselective hydrometalation of alkenes. D. functional theory calculations provide further insights into the reaction mechanism, suggesting a stereoselective migration insertion of alkenes with Ni(II)-H species. Finally, the origin of the regio- and enantioselectivities was also investigated.

ACS Catalysis published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 167479-01-8 belongs to class iodides-buliding-blocks, and the molecular formula is C8H16INO2, SDS of cas: 167479-01-8.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Boyle, Benjamin T.; Koniarczyk, J. Luke; McNally, Andrew published the artcile< Facile Pyridine SNAr Reactions via N-Phosphonium-Pyridinium Intermediates>, Safety of 4-Iodopyridin-3-ol, the main research area is pyridine nucleophilic aromatic substitution reaction halopyridine phosphine; phosphonium pyridinium intermediate; SNAr reaction; phosphonium salts; pyridines; pyridinium salts.

Here we report that N-phosphonium pyridinium intermediates are unusually reactive for pyridine SNAr reactions. Specifically, forming phosphonium salts from halopyridines typically requires elevated temperatures and Lewis acid additives. The alternative activation mode described in this paper permits C-P bond formation to occur at ambient temperatures in many cases, and functions across a broad range of substrates.

Synlett published new progress about Nucleophilic aromatic substitution reaction. 188057-20-7 belongs to class iodides-buliding-blocks, and the molecular formula is C5H4INO, Safety of 4-Iodopyridin-3-ol.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Olah, George A.; Wang, Qi; Sandford, Graham; Surya Prakash, G. K. published the artcile< Synthetic methods and reactions. 181. Iodination of deactivated aromatics with N-iodosuccinimide in trifluoromethanesulfonic acid (NIS-CF3SO3H) via in situ generated superelectrophilic iodine(I) trifluoromethanesulfonate>, Category: iodides-buliding-blocks, the main research area is iodination aromatic iodosuccinimide trifluoromethanesulfonic acid.

Deactivated aromatic compounds are readily iodinated by N-iodosuccinimide in trifluoromethanesulfonic acid (triflic acid) in good yields. Thus, PhNO2 was treated with NIS-CF3SO3H to give 3-iodonitrobenzene in 86% yield. The novel iodination is suggested to involve in situ generated and protosolvated iodine(I) trifluoromethanesulfonate.

Journal of Organic Chemistry published new progress about 2265-92-1. 2265-92-1 belongs to class iodides-buliding-blocks, and the molecular formula is C6H3F2I, Category: iodides-buliding-blocks.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Lu, Xiaofeng; Sun, Jibin; Liu, Yu; Shao, Jiafeng; Ma, Longfei; Zhang, Shangxi; Zhao, Jinlian; Shao, Yongliang; Zhang, Hao-Li; Wang, Zhaohui; Shao, Xiangfeng published the artcile< Decorating Tetrathiafulvalene (TTF) with Fluorinated Phenyls through Sulfur Bridges: Facile Synthesis, Properties, and Aggregation through Fluorine Interactions>, Quality Control of 2265-92-1, the main research area is fluorinated phenyl TTF derivative preparation aggregation CV UVVis; C-S coupling; TTF derivatives; electrochemistry; fluorine interactions; photochemistry.

Tetrathiafulvalene derivatives (TTF1-TTF9) bearing fluorinated Ph groups attached through the sulfur bridges have been synthesized by employing a copper-mediated C-S coupling reaction of C6H5-xFxI (x = 1, 2, 5) and a zinc-thiolate complex, (TBA)2[Zn(DMIT)2] (TBA = tetra-Bu ammonium, DMIT = 1,3-dithiole-2-thione-4,5-dithiolate), as the key step. Particularly, the selective synthesis of C6F5-substituted (TTF8) and C6F4-fused (TTF9) TTFs from C6F5I is disclosed. The physicochem. properties and crystal structures of these TTFs are fully investigated by UV/Vis absorption spectra, cyclic voltammetry, MO calculation, and single-crystal X-ray diffraction. The exchange of hydrogen vs. fluorine on the peripheral Ph groups show a notable influence on both the electronic and crystallog. natures of the resulting TTFs: (1) lowering both the HOMO and the LUMO energy levels, (2) modulating the electrochem. properties by regioselective and/or the degree of fluorination, (3) enhancing the driving forces of stacking by multiple fluorine interactions (F···S, C-F···π/πF, C-F···F-C, and C-F···H). This work indicates that the decoration with fluorinated phenyls holds promise to produce functional TTFs with novel electronic and aggregation features.

Chemistry – A European Journal published new progress about Aggregation. 2265-92-1 belongs to class iodides-buliding-blocks, and the molecular formula is C6H3F2I, Quality Control of 2265-92-1.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com