Month: October 2022

Computed Properties of C7H7IIn 2020 ,《Ligand-enabled gold-catalyzed 1,2-heteroarylation of alkenes》 was published in Chemical Communications (Cambridge, United Kingdom). The article was written by Tathe, Akash G.; Chintawar, Chetan C.; Bhoyare, Vivek W.; Patil, Nitin T.. The article contains the following contents:

By adopting the interplay between ligand-enabled Au(I)/Au(III) catalysis and the unique π-activation mode of gold complexes, a highly coveted 1,2-heteroarylation of alkenes was accomplished. The present ligand-enabled approach not only circumvents the requirement for strong sacrificial oxidants or photocatalysts but also operates under mild reaction conditions by utilizing simple and non-prefunctionalized aryl coupling partners. In the experiment, the researchers used 1-Iodo-4-methylbenzene(cas: 624-31-7Computed Properties of C7H7I)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Computed Properties of C7H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2017,Chemical Communications (Cambridge, United Kingdom) included an article by Yang, Xinglin; Shan, Gang; Yang, Zimo; Huang, Guiyi; Dong, Guoqiang; Sheng, Chunquan; Rao, Yu. Related Products of 41252-95-3. The article was titled 《One-pot synthesis of quaternary carbon centered cyclobutanes via Pd(II)-catalyzed cascade C(sp3)-H activations》. The information in the text is summarized as follows:

A novel approach toward quaternary carbon centered cyclobutanes through Pd(II)-catalyzed sequential intramol. methylene C-H alkylation and intermol. methine C-H bond arylation, alkenylation, alkylation, alkynylation, allylation, benzylation or alkoxylation is described. These quaternary carbon centered cyclobutanes could be further diversified through Pd(II)-catalyzed γ-C(sp3)-H bond activations. The synthetic utility of this novel approach was exemplified by its application to the synthesis of a bioactive small mol. Thus, e.g., cascade intramol. C-H alkylation/C-H arylation of 6-bromohexanamide containing the 8-aminoquinoline directing group (I) with 4-iodoacetophenone in presence of Pd(OAc)2/Ag2CO3 afforded cyclobutane II (75% isolated). In the experiment, the researchers used many compounds, for example, 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Related Products of 41252-95-3)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Related Products of 41252-95-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Photooxygenation inhibits tau amyloid formation》 were Suzuki, Takanobu; Hori, Yukiko; Sawazaki, Taka; Shimizu, Yusuke; Nemoto, Yu; Taniguchi, Atsuhiko; Ozawa, Shuta; Sohma, Youhei; Kanai, Motomu; Tomita, Taisuke. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Safety of 1-Iodopyrrolidine-2,5-dione The author mentioned the following in the article:

Tau amyloid formation and deposition are responsible for the onset of Alzheimer’s disease. In particular, the seeding activity of the tau protein plays an important role in the spreading of tau pathol. via its propagation in the human brain. Here we demonstrate that catalytic photo-oxygenation markedly suppresses tau seeding activity, resulting in the inhibition of amyloid formation, both in vitro and in cultured cells. In the part of experimental materials, we found many familiar compounds, such as 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Safety of 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Safety of 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Photoinduced Palladium-Catalyzed Carbofunctionalization of Conjugated Dienes Proceeding via Radical-Polar Crossover Scenario: 1,2-Aminoalkylation and Beyond》 was published in Journal of the American Chemical Society in 2020. These research results belong to Shing Cheung, Kelvin Pak; Kurandina, Daria; Yata, Tetsuji; Gevorgyan, Vladimir. Related Products of 301673-14-3 The article mentions the following:

In the presence of PdCl2, Xantphos, and AgNTf2, 1,3-dienes such as (E)-1-phenyl-1,3-butadiene underwent regioselective and diastereoselective photochem. carboamination reactions with alkyl iodides such as Me3SiCH2I and amines such as N-methylbenzylamine mediated by Cs2CO3 in THF under blue LED irradiation to yield allylic amines such as (E)-PhCH:CHCH(NMeBn)CH2CH2SiMe3. The method is modular and does not require exogenous photosensitizers or oxidants. 4-Methylphenol and di-Et malonate were used as nucleophiles in two reactions instead of amines, yielding an allylic ether and a homoallylmalonate as products. Inhibition of the reaction by TEMPO (with isolation of its trapping products), formation of radical dimerization products in the absence of AgNTf2, and formation of cinnamylated TEMPO from cinnamylpalladium Xantphos complexes and TEMPO support a mechanism involving a putative π-allyl palladium radical-polar crossover. In the experiment, the researchers used many compounds, for example, tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3Related Products of 301673-14-3)

tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Related Products of 301673-14-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《(ZrO)2Fe2O5 as an efficient and recoverable nanocatalyst in C-C bond formation》 was written by Ghorbani-Choghamarani, Arash; Mohammadi, Masoud; Taherinia, Zahra. Application In Synthesis of 1-Iodo-4-methylbenzeneThis research focused onzirconium ferrite recoverable nanocatalyst carbon bond formation. The article conveys some information:

In this paper, the synthesis and characterization of zirconium ferrite ((ZrO)2Fe2O5) magnetic nanoparticles (MNPs) and their application as a catalyst in C-C cross-coupling reaction will be described. The structure of the catalyst was studied by Fourier transform IR spectroscopy (FT-IR), SEM, energy dispersive spectrometry (EDS), X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), vibrating sample magnetometer (VSM) and ICP-OES anal. The resulting zirconium ferrite [(ZrO)2Fe2O5] was efficient for C-C coupling reactions, affording the desired products in good to excellent yields. Moreover, the catalyst could be easily recovered by magnetic separation and recycled for four times without significant loss of its catalytic activity. In the part of experimental materials, we found many familiar compounds, such as 1-Iodo-4-methylbenzene(cas: 624-31-7Application In Synthesis of 1-Iodo-4-methylbenzene)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Application In Synthesis of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《A new tricrystalline triblock terpolymer by combining polyhomologation and ring-opening polymerization. synthesis and thermal properties》 was written by Ladelta, Viko; Zapsas, George; Gnanou, Yves; Hadjichristidis, Nikos. Synthetic Route of C3H9IOSThis research focused ontricryst triblock terpolymer polyhomologation ring opening polymerization property. The article conveys some information:

New tricryst. triblock terpolymers, polyethylene-block-poly(ε-caprolactone)-block-poly(L-lactide) (PE-b-PCL-b-PLLA), were synthesized by ROP of ε-caprolactone (CL) and L-lactide (LLA) from linear ω-hydroxyl polyethylene (PE-OH) macroinitiators. The linear PE-OH macroinitiators were prepared by C1 polymerization of Me sulfoxonium methylide (polyhomologation). Tin(II) 2-ethylhexanoate was used as the catalyst for the sequential ROP of CL and LLA in one-pot polymerization at 85 °C in toluene (PE-OH macroinitiators are soluble in toluene at 80 °C). 1H NMR spectra confirmed the formation of PE-b-PCL-b-PLLA triblock terpolymers through the appearance of the characteristic proton peaks of each block. GPC traces showed the increase in the number average mol. weight from PE-OH macroinitiator to PE-b-PCL, and PE-b-PCL-b-PLLA corroborating the successful synthesis. The existence of three crystalline blocks was proved by DSC and XRD spectroscopy. The results came from multiple reactions, including the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6Synthetic Route of C3H9IOS)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Synthetic Route of C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Journal of Polymer Science, Part A: Polymer Chemistry included an article by Koronka, Daniel; Mahmoud, Ahmed Mohamed Ahmed; Miyatake, Kenji. Category: iodides-buliding-blocks. The article was titled 《Effect of crosslinking on the properties of partially fluorinated anion exchange membranes》. The information in the text is summarized as follows:

A series of crosslinked, ammonium-functionalized, and partially fluorinated copolymers have been prepared and evaluated as anion exchange membranes. In order to investigate the effect of crosslinking on the membrane properties, precursor copolymers containing chloromethyl groups were crosslinked with various aliphatic diamines followed by quaternization with monoamines. Crosslinking was effective in lowering water absorbability at no expense of high hydroxide ion conductivity of the membranes. By tuning the degree of crosslinking (20 mol %) and crosslinker chain length (C6 and C8), the highest ion conductivity of 73 mS/cm (at 80°C in water) was achieved. Furthermore, alk. stability of the membranes was also improved by the crosslinking; the remaining ion conductivity after the stability test (in 1 M potassium hydroxide at 80°C) was 8.2 mS/cm (after 1000 h) for the C6 crosslinked membrane and 1 mS/cm (after 500 h) for the uncrosslinked membrane, resp. The ammonium groups attached with the crosslinkers seemed more alk. stable than the uncrosslinked benzyltrimethylammonium groups, while the polymer main chain was intact under the harsh alk. conditions. © 2019 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym.Chem. 2019. In the experiment, the researchers used many compounds, for example, 1-Chloro-3-iodobenzene(cas: 625-99-0Category: iodides-buliding-blocks)

1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Category: iodides-buliding-blocksIodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Iridium-catalyzed B-H insertion of sulfoxonium ylides and borane adducts: a versatile platform to α-boryl carbonyls》 was written by Zhang, Shang-Shi; Xie, Hui; Shu, Bing; Che, Tong; Wang, Xiao-Tong; Peng, Dongming; Yang, Fan; Zhang, Luyong. Category: iodides-buliding-blocks And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:

Ir-catalyzed B-H bond insertion reactions of trimethylamine-borane and sulfoxonium ylides were demonstrated, furnishing α-boryl ketones in moderate to excellent yields in most cases (51 examples; up to 84%). This practical and scalable insertion reaction showed broad substrate scope, high functional-group compatibility and could be applied in late-stage modification of structurally complex drug compounds Further synthetic applications were also demonstrated. In the experimental materials used by the author, we found Trimethylsulfoxonium iodide(cas: 1774-47-6Category: iodides-buliding-blocks)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Partitioning effect of nitrogen catalyst into polymerizing particles on dispersion reversible chain transfer catalyzed polymerization (dispersion RTCP) of methyl methacrylate in supercritical carbon dioxide and organic solvents》 were Okubo, Masayoshi; Kitayama, Yukiya; Taniyama, Tomoya; Liu, Xiang; Zhang, Jianzheng; Shi, Hao. And the article was published in Journal of Polymer Science, Part A: Polymer Chemistry in 2019. COA of Formula: C4H4INO2 The author mentioned the following in the article:

Reversible chain transfer catalyzed polymerization (RTCP) in dispersion polymerization system (dispersion RTCP) of Me methacrylate (MMA) was performed with N-iodosuccimide (NIS) as a nitrogen catalyst in supercritical carbon dioxide (scCO2). The solubility of NIS in scCO2 can be controlled by tuning the pressure, and this led to promote NIS partitioning into polymerizing particles. As a result, the mol. weight distribution control was successfully improved by decreasing the NIS solubility in the medium by tuning the scCO2 at a low pressure of 20 MPa. On the other hand, at the same NIS concentration, a solution RTCP of MMA in toluene as a homogeneous polymerization system did not proceed with a controlled/living manner. The importance of NIS partitioning into the polymerizing particles was also confirmed in hexane as well as scCO2 medium. From these results, it was clarified that the NIS catalyst partitioning into the polymerizing particles as main polymerization loci is a key factor to control the mol. weight distribution in the dispersion RTCP of MMA in scCO2. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018. In the experimental materials used by the author, we found 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1COA of Formula: C4H4INO2)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. COA of Formula: C4H4INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Mkrtchyan, Satenik; Iaroshenko, Viktor O. published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Mechanochemical synthesis of aromatic sulfonamides》.Application of 625-99-0 The article contains the following contents:

A three-component Pd-catalyzed aminosulfonylation reaction of K2S2O5 and amines with aryl bromides or aromatic carboxylic acids was developed. This strategy was developed to utilize mech. energy and accommodate primary as well as secondary aliphatic and aromatic amines to provide a new shortcut to a wide range of sulfonamides. Studies on the scope and limitations of the reaction indicated its tolerance of a vast range of functional groups and many structural patterns. The reactions were scaled up to gram quantities. The experimental part of the paper was very detailed, including the reaction process of 1-Chloro-3-iodobenzene(cas: 625-99-0Application of 625-99-0)

1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.Application of 625-99-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com