Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. HPLC of Formula: 626-01-7.
Yang, Rui;Du, Wenhao;Yuan, Huan;Qin, Tianhong;He, Renxiao;Ma, Yanni;Du, Haiying research published 《 Synthesis and biological evaluation of 2-phenyl-4-aminoquinolines as potential antifungal agents》, the research content is summarized as follows. A series of 4-aminoquinolines I [R = N,N-dimethylamino, anilino, 1,2,4-triazol-1-yl, etc.] were designed, synthesized and evaluated for their antifungal activities against three phytopathogenic fungi in-vitro. All of the target compounds I were fully elucidated by 1H NMR, 13C NMR and HRMS spectra. The results indicated that most of the target compounds demonstrated significant activities against the tested fungi. Among them, compound I [R = 4-chloroanilino] exhibited more promising inhibitory activities against C. lunata (EC50 = 13.3μg/mL), P. grisea (EC50 = 14.4μg/mL) and A. alternate (EC50 = 15.6μg/mL), superior to azoxystrobin, a com. agricultural fungicide. The structure-activity relationship (SAR) revealed that the aniline moiety at position 4 of the quinoline scaffold played a key role in the potency of a compound And the substitution positions of the aniline moiety significantly influenced the activities. These encouraging results yielded a variety of 2-phenylquinolines bearing an aniline moiety acting as promising antifungal agents.
626-01-7, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.
3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., HPLC of Formula: 626-01-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com