Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Application of C5H4IN.
Wu, Xiaoqiang;Zheng, Purui;Li, Wanfang;Tao, XU research published 《 Reductive cross-coupling to access C-N bonds from aryl halides and diazoesters under dual nickel/photoredox-catalyzed conditions》, the research content is summarized as follows. A reductive cross-coupling reaction to access C(sp2)-N bonds via dual Ni/photoredox-catalyzed systems has been reported for the first time. By utilizing the easily available diazo compounds RC(=N2)C(O)2Et (R = C6H5, 3-FC6H4, 4-ClC6H4, etc.) as a nitrogen source, aryl hydrazones (E/Z)-ArNHN=C(R)C(O)2Et (Ar = C6H5, 2-naphthyl, 3-pyridyl, etc.) can be readily obtained under exceptionally mild conditions (visible light, ambient temperature, and no strong base). This method accommodates a broad scope of many functional groups and provides a novel route to deliver this type of product which can be further transformed into several kinds of nitrogen-containing heterocycles like 3,5-dimethyl-1-(4-trifluoromethylphenyl)-1H-pyrazole and 7-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-carbazole.
Application of C5H4IN, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.
3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com