In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Reference of 1120-90-7.
Wu, Fengtian;Yan, Fangming;Wu, Ling;Zhang, Caihong;Zeng, Rong;Sun, Yijia;Liu, Xiuping;Cui, Chunna;Wang, Peng research published 《 Reduction system “vitamin C/glycerol” promoted copper(II)-catalyzed N-arylation》, the research content is summarized as follows. The common access to forming C-N bonds is the copper-catalyzed Ullmann-type reaction. The relatively expensive and easily oxidized copper(I) is usually used in the reaction. The authors discovered that the “vitamin C/glycerol” reduction system could convert cheap and stable CuO to active low valence state copper species, as measured via XPS, to promote the C-N coupling reaction. In particular, 2-phenylindole, pyrrolo[1,2-a]quinoxaline, 1,2,4-triazole and 4-amino-7H-pyrrolo[2,3-d]pyrimidine derivatives were obtained in the presence of CuO and the “vitamin C/glycerol” reduction system. This method is a simple and cost-effective approach to the preparation of N-arylation products.
1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.
3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., Reference of 1120-90-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com